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肾肿瘤的微波消融:现状与发展趋势

Microwave ablation of renal tumors: state of the art and development trends.

作者信息

Floridi Chiara, De Bernardi Irene, Fontana Federico, Muollo Alessandra, Ierardi Anna Maria, Agostini Andrea, Fonio Paolo, Squillaci Ettore, Brunese Luca, Fugazzola Carlo, Carrafiello Gianpaolo

机构信息

Interventional Radiology Unit, University of Insubria, Varese, Italy,

出版信息

Radiol Med. 2014 Jul;119(7):533-40. doi: 10.1007/s11547-014-0426-8. Epub 2014 Jul 8.

Abstract

In the last decades an increased incidence of new renal tumor cases has been for clinically localized, small tumors <2.0 cm. This trend for small, low-stage tumors is the reflection of earlier diagnosis primarily as a result of the widespread and increasing use of non-invasive abdominal imaging modalities such as ultrasound, computerized tomography, and magnetic resonance imaging. Renal tumors are often diagnosed in elderly patients, with medical comorbidities whom the risk of surgical complications may pose a greater risk of death than that due to the tumor itself. In these patients, unsuitable for surgical approach, thermal ablation represents a valid alternative to traditional surgery. Thermal ablation is a less invasive, less morbid treatment option thanks to reduced blood loss, lower incidence of complications during the procedure and a less long convalescence. At present, the most widely used thermal ablative techniques are cryoablation, radiofrequency ablation and microwave ablation (MWA). MWA offers many benefits of other ablation techniques and offers several other advantages: higher intratumoral temperatures, larger tumor ablation volumes, faster ablation times, the ability to use multiple applicators simultaneously, optimal heating of cystic masses and tumors close to the vessels and less procedural pain. This review aims to provide the reader with an overview about the state of the art of microwave ablation for renal tumors and to cast a glance on the new development trends of this technique.

摘要

在过去几十年中,临床局限性小肿瘤(<2.0 cm)的新发肾肿瘤病例发病率有所上升。小的、低分期肿瘤的这种趋势主要反映了早期诊断,这主要是由于超声、计算机断层扫描和磁共振成像等非侵入性腹部成像方式的广泛应用和使用增加。肾肿瘤常在老年患者中被诊断出来,这些患者存在合并症,手术并发症的风险可能比肿瘤本身导致的死亡风险更大。在这些不适合手术治疗的患者中,热消融是传统手术的一种有效替代方法。热消融是一种侵入性较小、并发症较少的治疗选择,因为失血减少、手术过程中并发症发生率较低且恢复期较短。目前,应用最广泛的热消融技术是冷冻消融、射频消融和微波消融(MWA)。MWA具有其他消融技术的许多优点,还具有其他几个优势:肿瘤内温度更高、肿瘤消融体积更大、消融时间更快、能够同时使用多个消融器、对囊性肿块和靠近血管的肿瘤加热效果最佳以及手术疼痛较轻。本综述旨在为读者提供关于肾肿瘤微波消融技术现状的概述,并展望该技术的新发展趋势。

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