Elkholy Said S, Salem Hend A, Eweis Mohamed, Elsabee Maher Z
Department of Chemistry, Faculty of Science, Cairo University, Giza, Cairo 12613, Egypt.
Department of Chemistry, Faculty of Science, Cairo University, Giza, Cairo 12613, Egypt.
Int J Biol Macromol. 2014 Sep;70:199-207. doi: 10.1016/j.ijbiomac.2014.05.068. Epub 2014 Jun 2.
Three acyl derivatives of chitosan (CS) with different side chains were synthesized and their structures were characterized. Their swelling behavior was investigated. The antifungal behavior of these chitosan derivatives was investigated in vitro on the mycelial growth, sporulation and germination of conidia or sclerotia of the sugar-beet pathogens, Rhizoctonia solani K"uhn (AG2-2) and Sclerotium rolfsii Sacc. All the prepared derivatives had a significant inhibiting effect on the different stages of development on the germination of conidia or sclerotia of all the investigated fungi. In the absence of chitosan and its derivative, R. solani exhibited the fastest growth of the fungi studied.
合成了三种具有不同侧链的壳聚糖（CS）酰基衍生物，并对其结构进行了表征。研究了它们的溶胀行为。在体外研究了这些壳聚糖衍生物对甜菜病原菌立枯丝核菌（Rhizoctonia solani K"uhn，AG2-2）和齐整小核菌（Sclerotium rolfsii Sacc.）的分生孢子或菌核的菌丝生长、产孢和萌发的抗真菌行为。所有制备的衍生物对所有研究真菌的分生孢子或菌核萌发的不同发育阶段均有显著抑制作用。在没有壳聚糖及其衍生物的情况下，立枯丝核菌在所研究的真菌中生长最快。
