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[一名冠状动脉造影正常患者发生心肌梗死后室间隔破裂的罕见病例]

[An unusual case of postinfarction ventricular septal rupture in a patient with angiographically normal coronary arteries].

作者信息

Anchisi Chiara, Rossi Lidia, Bellacosa Ilaria, Di Ruocco Maria Virginia, Marino Paolo Nicola, Bongo Angelo Sante

出版信息

G Ital Cardiol (Rome). 2014 May;15(5):330-4. doi: 10.1714/1563.17037.

Abstract

Ventricular septal defect is a rare but potentially fatal complication of acute myocardial infarction. It usually occurs during the first episode of myocardial infarction, most often in patients with single vessel coronary artery disease and total occlusion of the culprit vessel, in the absence of an adequate collateral circulation. However, this complication is observed in patients with myocardial infarction with normal coronary arteries and its pathogenesis may be attributed to different mechanisms such as inflammation, hypercoagulable state or coronary vasospasm. We report the case of a 59-year-old female patient with anteroseptal myocardial infarction developed 4 days after admission, complicated by ventricular septal defect with signs of congestive heart failure and angiographically normal coronary arteries.

摘要

室间隔缺损是急性心肌梗死罕见但可能致命的并发症。它通常发生在心肌梗死的首次发作期间,最常见于单支冠状动脉疾病且罪犯血管完全闭塞、缺乏足够侧支循环的患者。然而,在冠状动脉正常的心肌梗死患者中也观察到这种并发症,其发病机制可能归因于不同的机制,如炎症、高凝状态或冠状动脉痉挛。我们报告一例59岁女性患者,入院4天后发生前间隔心肌梗死,并发室间隔缺损,伴有充血性心力衰竭体征,冠状动脉造影正常。

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