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[关于上海未经治疗的肺结核患者分离出的结核杆菌对豚鼠毒力的研究]

[Studies on the virulence in the guinea pig of tuberculosis bacilli isolated from patients with pulmonary tuberculosis before treatment in Shanghai].

作者信息

Yang D Y

出版信息

Zhonghua Jie He He Hu Xi Za Zhi. 1989 Feb;12(1):15-7, 61.

PMID:2500258
Abstract

The virulence in guinea-pig of 44 tubercle bacilli cultures from patients of tuberculosis before treatment in Shanghai and 26 from Tokyo has been studied for comparison. The results showed that the virulence of tubercle bacilli from Shanghai was lower than that from Tokyo. The difference was statistically significant (P less than 0.01). Among the 44 cultures from Shanghai high virulence accounted for 54.5%, low virulence 15.9% and middle virulence 29.5% whereas for the cultures from Tokyo high virulence accounted for 96.2% and middle virulence 3.8%.

摘要

对来自上海未经治疗的肺结核患者的44株结核杆菌培养物和来自东京的26株结核杆菌培养物在豚鼠身上的毒力进行了比较研究。结果显示,来自上海的结核杆菌毒力低于来自东京的。差异具有统计学意义(P小于0.01)。在来自上海的44株培养物中,高毒力的占54.5%,低毒力的占15.9%,中等毒力的占29.5%;而来自东京的培养物中,高毒力的占96.2%,中等毒力的占3.8%。

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