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弹力纤维瘤:一种罕见肿瘤实体切除后的临床结果

Elastofibroma: clinical results after resection of a rare tumor entity.

作者信息

Pilge Hakan, Hesper Tobias, Holzapfel Boris Michael, Prodinger Peter Michael, Straub Melanie, Krauspe Rüdiger

机构信息

Department of Orthopedics, University Clinic Dusseldorf , Germany.

Institute of Health and Biomedical Innovation, Queensland University of Technology , Brisbane, Australia.

出版信息

Orthop Rev (Pavia). 2014 Jun 16;6(2):5329. doi: 10.4081/or.2014.5329. eCollection 2014 Apr 22.

DOI:10.4081/or.2014.5329
PMID:25002937
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4083310/
Abstract

Elastofibroma (EF) is a benign proliferation of connective tissue and is typically located at the dorsal thoracic wall. Most patients complain about pain during motion in the shoulder girdle. The aim of our study was to evaluate the outcome after surgical treatment of EF. This study provides an overview of typical clinical findings, diagnostics and pathogenesis of this rare entity. In this retrospective study we analyzed data of 12 patients (6 male, 6 female) with EF treated in our institution between 2004 and 2012. The mean follow-up was 4.7 years (range: 5 months to 7.5 years). All tumors were found to be unilateral and all patients had a negative medical history for EF. Visual analogue scale and range of motion (ROM) was documented pre- and postoperatively. In all patients indication for surgical resection was pain or uneasiness during movement. There was no statistically significant difference in ROM of the shoulder between pre- and postoperatively but all patients reported significantly less pain after surgical resection. Patients benefited from tumor resection by a significant reduction of pain levels and improvement of the motion-dependent discomfort.

摘要

弹力纤维瘤(EF)是一种结缔组织的良性增生,通常位于胸壁背部。大多数患者抱怨肩胛带活动时疼痛。我们研究的目的是评估EF手术治疗后的效果。本研究概述了这种罕见疾病的典型临床表现、诊断方法和发病机制。在这项回顾性研究中,我们分析了2004年至2012年期间在我们机构接受治疗的12例EF患者(6例男性,6例女性)的数据。平均随访时间为4.7年(范围:5个月至7.5年)。所有肿瘤均为单侧,所有患者既往均无EF病史。术前和术后记录视觉模拟量表和活动范围(ROM)。所有患者手术切除的指征均为运动时疼痛或不适。术前和术后肩部ROM无统计学显著差异,但所有患者术后疼痛均明显减轻。肿瘤切除使患者疼痛水平显著降低,与运动相关的不适得到改善。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/34a1/4083310/9e7b8a15e118/or-2014-2-5329-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/34a1/4083310/079da1c6bca0/or-2014-2-5329-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/34a1/4083310/e7956a6bd779/or-2014-2-5329-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/34a1/4083310/6f8d8fdbd27d/or-2014-2-5329-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/34a1/4083310/5744ccd3de9f/or-2014-2-5329-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/34a1/4083310/9e7b8a15e118/or-2014-2-5329-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/34a1/4083310/079da1c6bca0/or-2014-2-5329-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/34a1/4083310/e7956a6bd779/or-2014-2-5329-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/34a1/4083310/6f8d8fdbd27d/or-2014-2-5329-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/34a1/4083310/5744ccd3de9f/or-2014-2-5329-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/34a1/4083310/9e7b8a15e118/or-2014-2-5329-g005.jpg

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[Open biopsy of bone and soft tissue tumors : guidelines for precise surgical procedures].[骨与软组织肿瘤的开放性活检:精确手术操作指南]
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Sensitivity and positive predictive value of magnetic resonance imaging in the diagnosis of elastofibroma dorsi: review of fourteen cases.
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Acta Orthop Traumatol Turc. 2017 Jan;51(1):7-11. doi: 10.1016/j.aott.2016.10.001. Epub 2016 Oct 22.
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Eur J Histochem. 2015 Feb 19;59(1):2459. doi: 10.4081/ejh.2015.2459.
磁共振成像在背部弹力纤维瘤诊断中的敏感性和阳性预测值:14 例病例回顾。
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