Zieliński Andrzej
Przegl Epidemiol. 2014;68(1):81-8, 161-8.
The historical review of medical activities draws attention how late in its very long history therapies of proven effectiveness were introduced. Author attributes it to the late development of methods which would be capable to determine the causal relations which would scientifically justified identification the causes and risk factors of diseases as well as checking the effectiveness of preventive and therapeutic procedures. Among the fundamental tools for scientific knowledge of the causes and mechanisms of diseases, the author indicates: achievements of basic science and the development of epidemiological methods used to study causal relationships. In the author's opinion the results of basic research are an essential source of variables among which, with an increased likelihood could be found the causes and risk factors of studied conditions, including diseases. The author also stresses the role of medical technology, which is the primary source of potential medicines, other therapeutic procedures and diagnostic methods whose effectiveness is tested in experimental epidemiological studies. Medical technologies create also tools for the development of basic sciences.
对医学活动的历史回顾引人关注的是,在其漫长的历史中,经证实有效的疗法是多么晚才被引入。作者将其归因于能够确定因果关系的方法发展较晚,而这种因果关系能够科学地确定疾病的病因和风险因素,并检验预防和治疗程序的有效性。在对疾病病因和机制进行科学认识的基本工具中,作者指出:基础科学的成就以及用于研究因果关系的流行病学方法的发展。作者认为,基础研究的结果是变量的重要来源,在这些变量中,更有可能找到所研究情况(包括疾病)的病因和风险因素。作者还强调了医学技术的作用,医学技术是潜在药物、其他治疗程序和诊断方法的主要来源,其有效性在实验性流行病学研究中得到检验。医学技术还为基础科学的发展创造了工具。