Makwana Bharat A, Vyas Disha J, Bhatt Keyur D, Jain Vinod K, Agrawal Yadvendra K
Department of Chemistry, School of Sciences, Gujarat University, Ahmedabad 380009, India.
Department of Chemistry, School of Sciences, Gujarat University, Ahmedabad 380009, India.
Spectrochim Acta A Mol Biomol Spectrosc. 2015 Jan 5;134:73-80. doi: 10.1016/j.saa.2014.05.044. Epub 2014 Jun 10.
Calix[4]resorcinarene polyhydrazide (CPH) protected water dispersible fluorescent silver nanaoparticles (AgNps) were prepared by one-pot method using water soluble CPH and AgNO₃. (CPH) bearing hydrazide group on its periphery acts as a reducing agent and its web type of structure as a stabilizing agent for the formation of calix protected silver nanoparticles (CPH-AgNps). CPH-AgNps were found to be highly stable over 120 days at room temperature and at varied pH. CPH-AgNps were characterized by UV/Vis-spectroscopy, particle size analyzer (PSA), transmission electron microscopy (TEM) and Energy dispersive X-ray analysis (EDX). Duly characterized nanoparticles were explored for their application as sensitive and selective fluorescent chemosensors for various metal ions. It was found that nanoparticles were selective and sensitive only for Fe(3+) ions with the linear range of detection from 0.1 μM to 10 μM. CPH-AgNps were also found to exhibit good antimicrobial activity when compared with standard Chloramphenicol. The selectivity and antimicrobial activity of CPH-AgNps suggests its potential use as a sensor for Fe(III) ions in ecosystems prone to industrial pollution and as an antimicrobial agent in biological applications.
采用一锅法，以水溶性杯[4]间苯二酚芳烃聚酰肼（CPH）和硝酸银（AgNO₃）制备了杯[4]间苯二酚芳烃聚酰肼（CPH）保护的水分散性荧光银纳米颗粒（AgNps）。外围带有酰肼基团的（CPH）充当还原剂，其网状结构作为杯芳烃保护的银纳米颗粒（CPH-AgNps）形成的稳定剂。发现CPH-AgNps在室温及不同pH值下120天内高度稳定。通过紫外可见光谱、粒度分析仪（PSA）、透射电子显微镜（TEM）和能量色散X射线分析（EDX）对CPH-AgNps进行了表征。对经过充分表征的纳米颗粒作为各种金属离子的灵敏且选择性荧光化学传感器的应用进行了探索。发现纳米颗粒仅对Fe(3+)离子具有选择性和灵敏性，检测线性范围为0.1 μM至10 μM。与标准氯霉素相比，CPH-AgNps还表现出良好的抗菌活性。CPH-AgNps的选择性和抗菌活性表明其在易受工业污染的生态系统中作为Fe(III)离子传感器以及在生物应用中作为抗菌剂的潜在用途。
