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Structure of the tetradecanucleotide d(CCCCGGTACCGGGG)2 as an A-DNA duplex.作为A-DNA双链体的十四聚体d(CCCCGGTACCGGGG)2的结构
Acta Crystallogr Sect F Struct Biol Cryst Commun. 2012 Apr 1;68(Pt 4):393-9. doi: 10.1107/S174430911200869X. Epub 2012 Mar 27.
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Acta Crystallogr D Biol Crystallogr. 2011 Apr;67(Pt 4):355-67. doi: 10.1107/S0907444911001314. Epub 2011 Mar 18.
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iMOSFLM: a new graphical interface for diffraction-image processing with MOSFLM.iMOSFLM：一种用于MOSFLM衍射图像处理的新图形界面。
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XDS.XDS.（这个词如果没有更多背景信息，很难准确翻译出更有意义的内容，直接保留原文是一种处理方式，或者音译为“克斯达斯”之类，但感觉都不太符合常规翻译场景，你可以补充更多关于这个词的信息以便我更准确翻译 ）
Acta Crystallogr D Biol Crystallogr. 2010 Feb;66(Pt 2):125-32. doi: 10.1107/S0907444909047337. Epub 2010 Jan 22.
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Coot: model-building tools for molecular graphics.Coot：分子图形的模型构建工具。
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Structure of d(CCCTAGGG): comparison with nine isomorphous octamer sequences reveals four distinct patterns of sequence-dependent intermolecular interactions.
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3DNA: a software package for the analysis, rebuilding and visualization of three-dimensional nucleic acid structures.3DNA：一个用于三维核酸结构分析、重建和可视化的软件包。
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The inherent properties of DNA four-way junctions: comparing the crystal structures of holliday junctions.DNA 四向连接体的固有特性：比较霍利迪连接体的晶体结构
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SFCHECK: a unified set of procedures for evaluating the quality of macromolecular structure-factor data and their agreement with the atomic model.SFCHECK：一套用于评估大分子结构因子数据质量及其与原子模型一致性的统一程序。
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10
Crystal structures of A-DNA duplexes.A-DNA双链体的晶体结构。
Biopolymers. 1997;44(1):45-63. doi: 10.1002/(SICI)1097-0282(1997)44:1<45::AID-BIP4>3.0.CO;2-#.

分辨率为1.65 Å时d(CCCCGGTACCGGGG)2的结构。

Structure of d(CCCCGGTACCGGGG)2 at 1.65 Å resolution.

作者信息

Purushothaman Monica, Varghese Anna, Mandal Pradeep Kumar, Gautham Namasivayam

机构信息

CAS in Crystallography and Biophysics, University of Madras, Guindy, Chennai, Tamil Nadu 600 025, India.

Institut Européen de Chimie et Biologie (IECB), 2 Rue Robert Escarpit, 33607 Pessac CEDEX, France.

出版信息

Acta Crystallogr F Struct Biol Commun. 2014 Jul;70(Pt 7):860-5. doi: 10.1107/S2053230X1401084X. Epub 2014 Jun 18.

DOI:10.1107/S2053230X1401084X
PMID:25005078
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4089521/
Abstract

The crystal structure of the tetradecanucleotide d(CCCCGGTACCGGGG)2 has previously been reported as an A-type double helix at a resolution of 2.5 Å in space group P41. Here, the structure of this sequence was determined at a significantly higher resolution of 1.65 Å in space group P4₁2₁2. The differences in crystal packing between the former and latter are described. The crystallographic asymmetric unit consists of one tetradecanucleotide duplex that spans more than one full turn of the A-helix. This structure allowed the unambiguous identification of solvent interactions.

摘要

十四聚体核苷酸d(CCCCGGTACCGGGG)₂的晶体结构先前已被报道为空间群P4₁中分辨率为2.5 Å的A型双螺旋结构。在此，该序列的结构在空间群P4₁2₁2中以1.65 Å的显著更高分辨率得以确定。描述了前后两者晶体堆积的差异。晶体学不对称单元由一个跨越A螺旋一圈多的十四聚体核苷酸双链体组成。该结构使得溶剂相互作用得以明确识别。