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胎粪污染羊水——小于胎龄儿的危险因素及围产期即刻结局

Meconium-stained amniotic fluid--risk factors and immediate perinatal outcomes among SGA infants.

作者信息

Pariente Gali, Peles C, Perri Zvi H, Baumfeld Yael, Mastrolia Salvatore Andrea, Koifman Arie, Weintraub Adi Y, Hershkovitz Reli

机构信息

Department of Obstetrics and Gynecology, Faculty of Health Sciences, Soroka University Medical Center, Ben-Gurion University of the Negev , Beer-Sheva , Israel .

出版信息

J Matern Fetal Neonatal Med. 2015 Jun;28(9):1064-7. doi: 10.3109/14767058.2014.942634. Epub 2014 Jul 30.

Abstract

OBJECTIVE

To detect factors that are associated with meconium-stained amniotic fluid (MSAF) among deliveries of small for gestational age (SGA) neonates and to identify perinatal outcomes of deliveries of SGA infants complicated with MSAF.

METHODS

A population-based study comparing deliveries of SGA neonates with and without MSAF was conducted. Deliveries occurred during the years 1988-2007 at the Soroka University Medical Center. Risk factors for MSAF among SGA infants were evaluated. Incidence of adverse pregnancy outcomes were compared between deliveries of SGA neonates with and without MSAF.

RESULTS

During the study period 9583 deliveries were of SGA neonates. Of these, 16.6% (n = 1597) were complicated with MSAF. Among SGA neonates, older maternal age, multiparty, lack of prenatal care and weight were significantly associated with MSAF. Having delivered an SGA infant with MSAF was associated with decreased rates of induction of labor and increased rates of labor dystocia, delivery by cesarean section and fetal distress. Using multivariable regression models, having delivered an SGA infant with MSAF was independently associated with fetal distress.

CONCLUSION

Among SGA neonates, deliveries complicated with MSAF are associated with additional adverse pregnancy outcomes.

摘要

目的

检测小于胎龄(SGA)新生儿分娩中与羊水胎粪污染(MSAF)相关的因素,并确定合并MSAF的SGA婴儿分娩的围产期结局。

方法

进行一项基于人群的研究,比较有和没有MSAF的SGA新生儿的分娩情况。分娩发生在1988 - 2007年期间的索罗卡大学医学中心。评估SGA婴儿中MSAF的危险因素。比较有和没有MSAF的SGA新生儿分娩中不良妊娠结局的发生率。

结果

在研究期间,9583例分娩为SGA新生儿。其中,16.6%(n = 1597)合并MSAF。在SGA新生儿中,产妇年龄较大、多产、缺乏产前护理和体重与MSAF显著相关。分娩出合并MSAF的SGA婴儿与引产率降低以及产程延长、剖宫产分娩和胎儿窘迫率增加有关。使用多变量回归模型,分娩出合并MSAF的SGA婴儿与胎儿窘迫独立相关。

结论

在SGA新生儿中,合并MSAF的分娩与额外的不良妊娠结局相关。

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