Gupta V, Bhatia B D, Mishra O P
Department of Pediatrics, Banaras Hindu University, Varanasi.
Indian Pediatr. 1996 Apr;33(4):293-7.
To find out the incidence, outcome as well as antenatal, intrapartum and neonatal attributes of meconium stained amniotic fluid (MSAF).
Prospective study.
Neonatal Unit of Hospital.
1426 live births occurring in 1500 consecutive deliveries, over one year period.
In all babies born through MSAF, thorough oropharyngeal suction as soon as the head was delivered followed by immediate intratracheal intubation and suctioning in infants depressed at birth.
204 (14.3%) deliveries had MSAF of which thick meconium was present in 141. Hepatitis in mother, fetal distress during labor and intrauterine growth retardation were significant factors associated with MSAF. One fifth of babies born through MSAF suffered severe birth anoxia compared to 5.6% in non-MSAF group. The consistency of meconium had direct bearing on the neonatal outcome. Severe birth asphyxia (SBA) occurred in 27.0 and 6.3% of babies with thick and thin meconium staining, respectively. Meconium aspiration syndrome was observed in 9 babies of thick meconium group and 8 of these were depressed at birth. All deaths occurred in thick meconium group and were associated with SBA.
Selective approach can be adopted for babies with MSAF reserving intratracheal suctioning at birth for depressed neonate or evidence of fetal distress in utero. Rest of the neonates only need careful observation after thorough oronasopharyngeal suctioning.
了解胎粪污染羊水(MSAF)的发生率、结局以及产前、产时和新生儿特征。
前瞻性研究。
医院新生儿科。
在一年期间内连续1500例分娩中的1426例活产儿。
对于所有通过MSAF出生的婴儿,头部娩出后立即进行彻底的口咽吸引,随后对出生时情况不佳的婴儿立即进行气管插管和吸引。
204例(14.3%)分娩存在MSAF,其中141例有浓稠胎粪。母亲患肝炎、分娩时胎儿窘迫和宫内生长迟缓是与MSAF相关的重要因素。通过MSAF出生的婴儿中有五分之一遭受严重出生缺氧,而非MSAF组为5.6%。胎粪的黏稠度与新生儿结局直接相关。浓稠和稀薄胎粪污染的婴儿中,严重出生窒息(SBA)的发生率分别为27.0%和6.3%。浓稠胎粪组有9例婴儿发生胎粪吸入综合征,其中8例出生时情况不佳。所有死亡均发生在浓稠胎粪组,且与SBA有关。
对于MSAF婴儿可采用选择性方法,仅对出生时情况不佳的新生儿或有宫内胎儿窘迫证据者在出生时进行气管吸引。其余新生儿在彻底口鼻咽吸引后仅需仔细观察。