初诊时伴有乳酸酸中毒的非霍奇金淋巴瘤：一例罕见肿瘤急症的病例报告
Non-Hodgkins lymphoma with lactic acidosis at presentation: A case report of a rare oncologic emergency.
作者信息
Kumar Arvind, Raina Vinod
机构信息
Department of Medical Oncology, Institute Rotary Cancer Hospital, All India Institute of Medical Sciences, New Delhi, India.
出版信息
Indian J Med Paediatr Oncol. 2014 Jan;35(1):83-5. doi: 10.4103/0971-5851.133728.
Abstract
Lactic acidosis (LA) has been reported to be associated with high grade lymphoma as a terminal event. Its causes are multi-factorial. It can either occur due to overproduction of lactic acid by rapidly dividing tumor or due to its underutilization due to involvement of liver by lymphomatous deposits. The prognosis of lymphoma associated with LA is dismal. We present a patient of non-Hodgkins lymphoma (NHL) who presented with LA, after an initial response succumbed.
摘要
据报道，乳酸酸中毒（LA）作为终末期事件与高级别淋巴瘤有关。其病因是多因素的。它可能是由于快速增殖的肿瘤过度产生乳酸，或者是由于淋巴瘤沉积物累及肝脏导致乳酸利用不足所致。与LA相关的淋巴瘤预后不佳。我们报告一例非霍奇金淋巴瘤（NHL）患者，该患者出现LA，在最初有反应后最终死亡。
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本文引用的文献
1
Type B lactic acidosis secondary to malignancy: case report, review of published cases, insights into pathogenesis, and prospects for therapy.继发于恶性肿瘤的B型乳酸酸中毒：病例报告、已发表病例回顾、发病机制见解及治疗前景
ScientificWorldJournal. 2011 Jul 7;11:1316-24. doi: 10.1100/tsw.2011.125.
2
Severe lactic acidosis in a patient with B-cell lymphoma: a case report and review of the literature.一名B细胞淋巴瘤患者的严重乳酸酸中毒：病例报告及文献综述
Case Rep Med. 2009;2009:534561. doi: 10.1155/2009/534561. Epub 2010 Jan 4.
3
Glucose availability regulates IFN-gamma production and p70S6 kinase activation in CD8+ effector T cells.葡萄糖的可利用性调节CD8 +效应T细胞中γ干扰素的产生和p70S6激酶的激活。
J Immunol. 2005 Apr 15;174(8):4670-7. doi: 10.4049/jimmunol.174.8.4670.
4
[On the facultative anaerobiosis of cancer cells and its use in chemotherapy].
Munch Med Wochenschr. 1961 Dec 22;103:2504-6.
5
Lactic acidosis: a metabolic complication of hematologic malignancies: case report and review of the literature.乳酸酸中毒：血液系统恶性肿瘤的一种代谢并发症：病例报告及文献综述
Cancer. 2001 Nov 1;92(9):2237-46. doi: 10.1002/1097-0142(20011101)92:9<2237::aid-cncr1569>3.0.co;2-9.
6
Transport of lactate and other monocarboxylates across mammalian plasma membranes.乳酸及其他单羧酸盐在哺乳动物细胞膜间的转运。
Am J Physiol. 1993 Apr;264(4 Pt 1):C761-82. doi: 10.1152/ajpcell.1993.264.4.C761.
7
Analysis of oxygen transport to tumor tissue by microvascular networks.通过微血管网络对肿瘤组织氧输送的分析。
Int J Radiat Oncol Biol Phys. 1993 Feb 15;25(3):481-9. doi: 10.1016/0360-3016(93)90070-c.
8
Definition of clinically relevant lactic acidosis in patients with internal diseases.内科疾病患者临床相关乳酸酸中毒的定义。
Am J Clin Pathol. 1983 Oct;80(4):484-9. doi: 10.1093/ajcp/80.4.484.
9
Metabolic effects of sodium bicarbonate in hypoxic lactic acidosis in dogs.碳酸氢钠对犬缺氧性乳酸酸中毒的代谢影响
Am J Physiol. 1985 Nov;249(5 Pt 2):F630-5. doi: 10.1152/ajprenal.1985.249.5.F630.
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