Beugeling Maaike, Ewing-Graham Patricia C, Mzallassi Zineb, van Doorn Helena C
Department of Gynecological Oncology, Erasmus Medical Center, Rotterdam, Cancer Institute, P.O. Box 5201, 3008 AE Rotterdam, The Netherlands ; Department of Radiation Therapy, Erasmus Medical Center, Cancer Institute, P.O. Box 5201, 3008 AE Rotterdam, The Netherlands.
Department of Pathology, Erasmus Medical Center, P.O. Box 2040, 3000 CA Rotterdam, The Netherlands.
ISRN Surg. 2014 Mar 25;2014:385386. doi: 10.1155/2014/385386. eCollection 2014.
Hypothesis. Pathology slide review in vulvar cancer is only necessary in a restricted number of cases. Methods. A retrospective chart review of all cases of vulvar cancer treated in a tertiary centre between January 1, 2000, and April 1, 2006. Histopathology reports from the referring and tertiary centre were compared. Results. 121 pathology reports from 112 patients were reviewed. Of the original reports, 56% were deemed adequate, commenting on tumor type and depth of infiltration; of the reviews, 83% were adequate. Conclusion. There were no discrepancies that influenced patient management. We suggest that vulvar cancer biopsies need to be reviewed only when the tumor is less than 10 mm in linear extension, when the infiltration is 1 mm or less, when there is no residual tumor on inspection, and in any nonsquamous cancer.
假设。仅在有限数量的病例中需要对外阴癌进行病理切片复查。方法。对2000年1月1日至2006年4月1日在一家三级中心接受治疗的所有外阴癌病例进行回顾性病历审查。比较了转诊中心和三级中心的组织病理学报告。结果。对112例患者的121份病理报告进行了审查。在原始报告中,56%被认为是充分的,对肿瘤类型和浸润深度进行了评论;在复查报告中,83%是充分的。结论。没有影响患者管理的差异。我们建议,仅当肿瘤线性延伸小于10毫米、浸润为1毫米或更小、检查时无残留肿瘤以及任何非鳞状细胞癌时,才需要对外阴癌活检进行复查。