Wei Han, Xiaofeng Huang, Yang Zheng, Zhiyong Wang
From the *Department of Oral and Maxillofacial Surgery, †Central Laboratory of Stomatology, and ‡Department of Pathology, Stomatological Hospital Affiliated Medical School, Nanjing University, Nanjing, People's Republic of China.
J Craniofac Surg. 2014 Jul;25(4):e326-8. doi: 10.1097/SCS.0000000000000592.
The purpose of this study was to assess the diagnosis, treatment, and prognosis of oncocytic carcinoma. This was a retrospective study of 7 patients with oncocytic carcinoma according to the 2005 World Health Organization classification guidelines who underwent 1 or more surgical interventions within the last 20-year period from 1992 to 2012. The lesions were located in the parotid glands in 5 patients, the submandibular glands in 1 patient, and the sublingual gland in 1 patient. One of the patients experienced tumor recurrence after conservative surgery before he was admitted to our department. Five patients were treated with a total parotidectomy, and 3 underwent additional neck dissection. Only 1 patient died, as a result of pulmonary metastases. After a follow-up period of 3 to 198 months, no recurrences were found in any of the surviving patients. On the basis of our experience, poorly differentiated oncocytic carcinoma should be treated with the total resection of the affected salivary gland and a selective neck dissection. Patients with oncocytic carcinoma should remain in long-term follow-up.
本研究的目的是评估嗜酸细胞癌的诊断、治疗及预后。这是一项回顾性研究，根据2005年世界卫生组织分类指南，对1992年至2012年过去20年内接受了1次或更多次手术干预的7例嗜酸细胞癌患者进行研究。病变位于5例患者的腮腺、1例患者的下颌下腺和1例患者的舌下腺。其中1例患者在保守手术后出现肿瘤复发，随后入住我科。5例患者接受了腮腺全切术，3例患者接受了额外的颈部清扫术。仅1例患者因肺转移死亡。经过3至198个月的随访，所有存活患者均未发现复发。根据我们的经验，低分化嗜酸细胞癌应采用患侧涎腺全切术及选择性颈部清扫术进行治疗。嗜酸细胞癌患者应接受长期随访。
