Yan Jianhua, Li Yongping
From the State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, People's Republic of China.
J Craniofac Surg. 2014 Jul;25(4):e348-9. doi: 10.1097/SCS.0000000000000774.
PURPOSE/BACKGROUND: An orbital cavernous hemangioma is composed of large, ectatic, endothelium-lined, blood-filled spaces. Inflammatory cells, such as lymphocytes, are rarely found in the interstitium. In this case report, a Chinese woman with an unusual presentation of an orbital cavernous hemangioma resulting from a substantial infiltration of inflammatory cells is presented.
Data (unusual findings of clinical features, computed tomography, and ultrasonography examination) from a patient with an orbital cavernous hemangioma showing an obvious infiltration of inflammatory cells in the interstitium are presented.
A 45-year-old Chinese woman presented with a painless slow-growing orbital tumor in the left eye that was present for 9 years. There was a smooth, well-defined, moderate-density, tenderless mass measuring 2.5 × 3.0 cm within the medial and inferior orbit. Her left eye was superolaterally displaced. Exophthalmometry showed a 7-mm proptosis of the left eye. Computed tomography showed an ovoid orbital soft-tissue mass with a few punctate calcifications, located in the inferomedial aspect of the left orbit. Color Doppler showed a moderate blood supply within the tumor. A purplish, spongy, encapsulated 2.5 × 3.0 × 3.0 cm mass, which was moderately adherent to surrounding tissues, was completely removed by an anterior orbitotomy. No surgical complication occurred. Histopathologic examination confirmed the diagnosis of an orbital cavernous hemangioma. There was an obvious infiltration of inflammatory cells within the interstitium of the mass.
As a result of the infiltration of inflammatory cells within this case of orbital cavernous hemangioma, the atypical clinical manifestation makes it difficult to arrive at a correct presurgical diagnosis.
目的/背景:眼眶海绵状血管瘤由大的、扩张的、内衬内皮的、充满血液的间隙组成。间质中很少发现炎症细胞,如淋巴细胞。在本病例报告中,介绍了一名患有眼眶海绵状血管瘤的中国女性,其表现不寻常,间质中有大量炎症细胞浸润。
报告了一名眼眶海绵状血管瘤患者的数据(临床特征、计算机断层扫描和超声检查的异常发现),该患者间质中有明显的炎症细胞浸润。
一名45岁中国女性,左眼有无痛性缓慢生长的眼眶肿物,已存在9年。在内侧和下眼眶内有一个光滑、边界清晰、中等密度、无压痛的肿物,大小为2.5×3.0 cm。她的左眼向外上移位。眼球突出度测量显示左眼突出7 mm。计算机断层扫描显示左眼眶内下象限有一个椭圆形眼眶软组织肿物,伴有少量点状钙化。彩色多普勒显示肿瘤内血供中等。通过前路眼眶切开术完整切除了一个紫色、海绵状、有包膜、大小为2.5×3.0×3.0 cm、与周围组织中度粘连的肿物。未发生手术并发症。组织病理学检查确诊为眼眶海绵状血管瘤。肿物间质中有明显的炎症细胞浸润。
由于该例眼眶海绵状血管瘤中有炎症细胞浸润,非典型的临床表现使得术前难以做出正确诊断。