Bezjak Miran, Sesar Patricija, Ulamec Monika, Pavić Ivana, Mijić August, Spajić Borislav, Kruslin Bozo
Acta Med Croatica. 2013 Jun;67(3):255-8.
Myelolipoma is a rare, benign, non-functioning tumor most frequently located in the adrenal cortex. It consists of mature fatty tissue with components of hematopoietic tissue in different proportions. There are certain ambiguities related to the diagnosis and therapy of myelolipoma, and it is therefore important to keep in view all the aspects of the lesion and the circumstances in which it develops. This paper presents a series of 15 patients with myelolipoma diagnosed at the Ljudevit Jurak Department of Pathology, Sestre milosrdnice University Hospital Center. Out of 15 patients, 10 were men (one of them with bilateral tumor) aged 41 to 73, and 5 were women aged 51 to 54. Macroscopically, the tumors were oval, encapsulated, yellowish, soft masses located in the adrenal glands. The diameter of the tumors ranged between 0.5 and 13.9 cm. Microscopically, they consisted of multiplied mature adipose cells combined with myeloid tissue composed largely of megakaryocytes, erythroid cells and lymphocytes. In all patients, the postoperative course was uneventful with no recurrences.
髓脂肪瘤是一种罕见的良性无功能肿瘤，最常位于肾上腺皮质。它由成熟脂肪组织和不同比例的造血组织成分组成。髓脂肪瘤的诊断和治疗存在一定的模糊性，因此重要的是要全面考虑病变的各个方面及其发生的情况。本文介绍了在斯雷姆斯卡·米洛什德尼察大学医院中心卢德维特·尤拉克病理科诊断的15例髓脂肪瘤患者。15例患者中，10例为男性（其中1例为双侧肿瘤），年龄在41岁至73岁之间，5例为女性，年龄在51岁至54岁之间。宏观上，肿瘤为椭圆形、有包膜、淡黄色、质地柔软的肿块，位于肾上腺。肿瘤直径在0.5厘米至13.9厘米之间。微观上，它们由增殖的成熟脂肪细胞与主要由巨核细胞、红细胞和淋巴细胞组成的髓样组织结合而成。所有患者术后病程平稳，无复发。
