J Cutan Med Surg. 2014 Jul-Aug;18(4):275-6. doi: 10.2310/7750.2013.13128.
A 36-year-old woman with well-controlled type 1 diabetes mellitus reported hyperglycemia (plasma glucose peaked at 21.3 mmol/L) after her first injection with intralesional triamcinolone acetonide for alopecia areata.
Intralesional corticosteroids are used to maximize local effect while presumably minimizing systemic complications. This adverse effect is an important consideration when treating patients with insulin-dependent diabetes mellitus, and it would be reasonable to counsel patients of such a possibility.
一位 36 岁女性,患有 1 型糖尿病,血糖控制良好。她首次接受皮损内曲安奈德注射治疗斑秃后出现高血糖(血糖峰值达 21.3mmol/L)。
皮损内皮质类固醇用于最大限度地发挥局部作用,同时可能最大限度地减少全身并发症。当治疗依赖胰岛素的糖尿病患者时,这种不良反应是一个重要的考虑因素,告知患者这种可能性是合理的。