Memari Faramarz, Hassannia Fatemeh
Department of Otorhinolaryngology, Head and Neck Surgery. Iran University of Medical Sciences. Hazrate Rasul Medical Center, Tehran, Iran.
Iran J Otorhinolaryngol. 2014 Jul;26(76):129-33.
We investigated the effect of intratympanic dexamethasone on control of tinnitus and hearing loss in patients with Menier's disease.
100 consecutive patients with a diagnosis of Menier's disease according to the 1995 criteria of The American Academy of Otolaryngology - Head and Neck Surgery (AAO-HNS) who remained symptomatic despite medical therapy were assigned to receive intratympanic dexamethasone. The results were assessed with respect to changes in hearing symptoms and tinnitus.
Hearing improvement and improvement in SDS was observed in 52% and 35% of patients, respectively. Tinnitus score was improved in 57% of patients. There was no relationship between age, sex, duration of disease, unilaterality of disease, or response to therapy.
Intratympanic dexamethasone may be effective in the symptomatic control of hearing loss and tinnitus in Menier's disease.
我们研究了鼓室内注射地塞米松对梅尼埃病患者耳鸣及听力损失控制的效果。
100例根据美国耳鼻咽喉头颈外科学会(AAO-HNS)1995年标准诊断为梅尼埃病且尽管接受了药物治疗仍有症状的连续患者被分配接受鼓室内注射地塞米松。根据听力症状和耳鸣的变化对结果进行评估。
分别有52%和35%的患者听力得到改善,症状自评量表(SDS)得分有所改善。57%的患者耳鸣评分得到改善。年龄、性别、病程、疾病的单侧性或治疗反应之间均无关联。
鼓室内注射地塞米松可能对梅尼埃病患者听力损失和耳鸣的症状控制有效。