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累积镇痛药物消耗评分(CACS):一种新评分的评估,该评分将术后镇痛药物消耗描述为术后疼痛和手术侵袭性的替代参数。

The cumulative analgesic consumption score (CACS): evaluation of a new score to describe postsurgical analgesic consumption as a surrogate parameter for postoperative pain and invasiveness of surgical procedures.

作者信息

Schoenthaler Martin, Miernik Arkadiusz, Offner Klaus, Karcz Wojciech Konrad, Hauschke Dieter, Sevcenco Sabina, Kuehhas Franklin Emmanuel, Bach Christian, Buchholz Noor, Wilhelm Konrad

机构信息

Department of Urology, , University Medical Center Freiburg, Freiburg, Germany.

1Department of Urology, , University Medical Center Freiburg, Freiburg, Germany.

出版信息

Int Braz J Urol. 2014 May-Jun;40(3):330-6. doi: 10.1590/S1677-5538.IBJU.2014.03.06.

Abstract

OBJECTIVE

To validate and evaluate the applicability of a new score to describe postsurgical analgesic consumption in urological and surgical patients across different categories of pain medications and the invasiveness of medical interventions.

MATERIALS AND METHODS

The cumulative analgesic consumption score (CACS) was determined for two cohorts of patients split into three groups with surgeries involving clinically distinct levels of invasiveness (n = 2 x 60). Nonparametric statistical analyses were performed to determine differences between the CACS among the different groups and to assess the correlation between CACS and numeric rating scale (NRS) values for pain intensity.

RESULTS

The score was determined for postoperative days 1 and 2 and revealed median scores of 0 (0-11), 3 (0-22) and 10 (6-17) for UA (urological patients from group A), UB (group B) and UC (group C), respectively, and 4 (0-20), 8 (0-38) and 17 (7-68) for SA (surgical patients from group A, SB (group B) and SC (group C), respectively. CACS enabled reliable differentiation between groups involving different levels of invasiveness (p < 0.001). CACS and peak NRS values showed variable degrees of correlation, as expressed by levels of significance ranging from p < 0.001 to p = 0.34 (NS).

CONCLUSIONS

The CACS is a valid and easily applicable tool to describe postsurgical analgesic consumption in urological and surgical patients. It can be used as a surrogate parameter to assess postsurgical pain and the invasiveness of surgical procedures. These aspects may be measured to compare surgical procedures, in both clinical trials and clinical practice settings.

摘要

目的

验证并评估一种新评分在描述泌尿外科和外科手术患者不同类别止痛药物的术后止痛药物消耗量以及医疗干预侵入性方面的适用性。

材料与方法

将两组患者分为三组,每组手术的侵入性水平在临床上各不相同(n = 2×60),确定其累积止痛药物消耗评分(CACS)。进行非参数统计分析,以确定不同组之间CACS的差异,并评估CACS与疼痛强度数字评分量表(NRS)值之间的相关性。

结果

确定了术后第1天和第2天的评分,结果显示,A组泌尿外科患者(UA)、B组(UB)和C组(UC)的中位评分分别为0(0 - 11)、3(0 - 22)和10(6 - 17),A组外科手术患者(SA)、B组(SB)和C组(SC)的中位评分分别为4(0 - 20)、8(0 - 38)和17(7 - 68)。CACS能够可靠地区分不同侵入性水平的组(p < 0.001)。CACS与NRS峰值显示出不同程度的相关性,显著性水平范围为p < 0.001至p = 0.34(无显著性差异)。

结论

CACS是一种有效且易于应用的工具,可用于描述泌尿外科和外科手术患者的术后止痛药物消耗量。它可以作为评估术后疼痛和手术侵入性的替代参数。在临床试验和临床实践中,可通过测量这些方面来比较手术操作。

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