Cukurova Ibrahim, Gümüşsoy Murat, Kaptaner Suat, Uğur Omer, Iber Metin, Arslan Ilker Burak, Uluyol Sinan
Department of Otolaryngology, Tepecik Training and Research Hospital, 35460 Tepecik, İzmir, Turkey.
Kulak Burun Bogaz Ihtis Derg. 2014 May-Jun;24(3):177-80. doi: 10.5606/kbbihtisas.2014.77200.
Primary squamous cell carcinoma of the nasal septum is an extremely rare malignancy. In this article, we report a case of 52-year-old female with a complaint of nasal obstruction along with occasional nasal bleeding for one year. Endoscopy showed a 2.5x2 cm perforation originating from the anterior nasal septum. Incisional biopsy result was reported as squamous cell carcinoma. The tumor was removed by functional endoscopic surgery. Histopathological examination revealed squamous cell carcinoma with safe surgery borders. No recurrence and complications were noticed after one year of follow-up. The functional impact of the treatment with high mortality rates highlights the importance of early diagnosis. We recommend the differential diagnosis of septal perforation and early wide surgical excision for such cases.
鼻中隔原发性鳞状细胞癌是一种极为罕见的恶性肿瘤。在本文中，我们报告了一例52岁女性患者，主诉鼻塞并伴有偶尔鼻出血一年。内镜检查显示从前鼻中隔起源的一个2.5×2厘米的穿孔。切开活检结果报告为鳞状细胞癌。通过功能性内镜手术切除肿瘤。组织病理学检查显示为具有安全手术切缘的鳞状细胞癌。随访一年后未发现复发和并发症。高死亡率治疗的功能影响凸显了早期诊断的重要性。对于此类病例，我们建议对鼻中隔穿孔进行鉴别诊断并早期广泛手术切除。
