通过自组装制备的表位印记聚醚砜微珠用于从血浆蛋白质组中捕获目标蛋白质。
Epitope imprinted polyethersulfone beads by self-assembly for target protein capture from the plasma proteome.
作者信息
Yang Kaiguang, Liu Jianxi, Li Senwu, Li Qinran, Wu Qi, Zhou Yuan, Zhao Qun, Deng Nan, Liang Zhen, Zhang Lihua, Zhang Yukui
机构信息
CAS Key Lab of Separation Sciences for Analytical Chemistry, National Chromatographic R&A Center, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, 116023, China.
出版信息
Chem Commun (Camb). 2014 Aug 28;50(67):9521-4. doi: 10.1039/c4cc03428g.
Polymer self-assembly was developed as an epitope imprinting strategy involving facile processes and high recognition site density. As a model, transferrin epitope imprinted polyethersulfone (PES) beads were successfully fabricated using this technique. The imprinted beads demonstrated excellent selectivity toward the transferrin epitope and transferrin even in the real sample.
聚合物自组装作为一种表位印迹策略得到发展，该策略涉及简便的过程和高识别位点密度。作为一个模型，使用该技术成功制备了转铁蛋白表位印迹的聚醚砜（PES）珠。即使在实际样品中，印迹珠对转铁蛋白表位和转铁蛋白也表现出优异的选择性。
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