Preoperative intra-arterial infusion chemotherapy for patients with bladder cancer.

The effectiveness of the preoperative intra-arterial infusion chemotherapy was studied in 27 patients with muscular invasive bladder cancer. Severe histological destruction of tumor structures was found in 7 cases in the removed bladder at surgery. For these cases, 3-year and 5-year survival rates were 100%. On the other hand, for cases whose destruction of tumor structures was of mild degree or less, 3-year survival rates were 51.9-57.1%. No serious side effect was observed. This preoperative therapy was thought to offer advantages for some patients with muscular invasive bladder cancer.