Boudjerra Nadia, Perry Anamarija M, Audouin Josée, Diebold Jacques, Nathwani Bharat N, MacLennan Kenneth A, Müller-Hermelink Hans K, Bast Martin, Boilesen Eugene, Armitage James O, Weisenburger Dennis D
Department of Clinical Hematology, University Pierre and Marie Curie , Algiers , Algeria.
Leuk Lymphoma. 2015 Apr;56(4):965-70. doi: 10.3109/10428194.2014.939967. Epub 2014 Aug 20.
The relative distribution of non-Hodgkin lymphoma (NHL) subtypes differs markedly around the world. The aim of this study was to report this distribution in Algeria. A panel of four hematopathologists classified 197 consecutive cases according to the World Health Organization classification, including 87.3% B-cell and 12.7% T- or natural killer (NK)-cell NHLs. This series was compared with similar cohorts from Western Europe (WEU) and North America (NA). Algeria had a significantly higher frequency of diffuse large B-cell lymphoma (DLBCL: 52.8%) and a lower frequency of follicular lymphoma (FL: 13.2%) compared with WEU (DLBCL: 32.2%; FL: 20.0%) and NA (DLBCL: 29.3%; FL: 33.6%). The frequency of mantle cell lymphoma was lower in Algeria (2.5%) compared with WEU (8.3%). Smaller differences were also found among the NK/T-cell lymphomas. In conclusion, we found important differences between Algeria and Western countries, and further epidemiologic studies are needed to explain these differences.
非霍奇金淋巴瘤（NHL）亚型的相对分布在世界各地存在显著差异。本研究的目的是报告阿尔及利亚的这种分布情况。由四位血液病理学家组成的小组根据世界卫生组织分类法对197例连续病例进行了分类，其中B细胞非霍奇金淋巴瘤占87.3%，T或自然杀伤（NK）细胞非霍奇金淋巴瘤占12.7%。该系列病例与来自西欧（WEU）和北美的类似队列进行了比较。与西欧（弥漫性大B细胞淋巴瘤：32.2%；滤泡性淋巴瘤：20.0%）和北美（弥漫性大B细胞淋巴瘤：29.3%；滤泡性淋巴瘤：33.6%）相比，阿尔及利亚弥漫性大B细胞淋巴瘤（DLBCL：52.8%）的发生率显著更高，滤泡性淋巴瘤（FL：13.2%）的发生率更低。与西欧（8.3%）相比，阿尔及利亚套细胞淋巴瘤的发生率更低（2.5%）。在NK/T细胞淋巴瘤中也发现了较小的差异。总之，我们发现阿尔及利亚与西方国家之间存在重要差异，需要进一步的流行病学研究来解释这些差异。
