Higashi F, Nakamura M, Maruyama T, Nakamura Y, Arikawa K, Funatsu Y, Ogawa J, Katsu M
Kansenshogaku Zasshi. 1989 Jan;63(1):79-82. doi: 10.11150/kansenshogakuzasshi1970.63.79.
Legionnaires' disease is primarily a respiratory disorder, but recently several cases with extrapulmonary manifestations are reported. We report a case of Legionnaires' disease associated with pneumonia, diarrhea, central nerve disorders and rhabdomyolysis. The pathogenesis of rhabdomyolysis in Legionnaires' disease remains speculative. Endotoxin isolated from Legionella pneumophila may play a role in the pathogenesis of the myonecrosis. An additional factor that might contribute to rhabdomyolysis in this case is severe dehydration induced by diarrhea. Pneumonia with elevated CPK levels and myoglobinuria may suggest Legionnaires' disease.
军团病主要是一种呼吸系统疾病，但最近有几例出现肺外表现的病例报告。我们报告一例与肺炎、腹泻、中枢神经紊乱和横纹肌溶解相关的军团病。军团病中横纹肌溶解的发病机制仍属推测。从嗜肺军团菌分离出的内毒素可能在肌坏死的发病机制中起作用。该病例中可能导致横纹肌溶解的另一个因素是腹泻引起的严重脱水。肌酸磷酸激酶水平升高和肌红蛋白尿的肺炎可能提示军团病。
