Celikagi Cemil, Genc Abdurrahman, Bal Ahmet, Ucok Kagan, Turamanlar Ozan, Ozkececi Z Taner, Yalcinkaya Hatice, Coban Necip F, Yorulmaz Sueda
Departments of aPhysiology bGeneral Surgery cAnatomy, Faculty of Medicine, Afyon Kocatepe University, Afyonkarahisar dDepartment of Physiology, Faculty of Medicine, Dumlupinar University, Kutahya, Turkey.
Eur J Gastroenterol Hepatol. 2014 Oct;26(10):1133-8. doi: 10.1097/MEG.0000000000000159.
The aim of this study was to investigate the daily energy expenditure; resting metabolic rate (RMR); health-related physical fitness parameters such as maximal aerobic capacity, muscle strength, and flexibility; pulmonary function tests (PFTs); and body composition and body fat distribution changes in patients with cholelithiasis, and to compare them with healthy controls.
Thirty female patients with cholelithiasis and 30 controls were included in this study. Daily physical activity was monitored using a metabolic Holter and the maximal aerobic capacity was estimated using the Astrand submaximal exercise protocol. The body composition was established with a bioelectrical impedance analyzer. RMR, PFTs, strength, flexibility, circumference, and skinfold measurements were also carried out.
Maximal aerobic capacity, trunk flexibility, daily moderate activity duration, daily vigorous activity duration, total energy expenditure, RMR, PFT, lean body mass, adiposity, and body fat distribution values were not significantly different between the patients and the controls. The cholelithiasis patients had lower daily step numbers, handgrip strength, and back-leg strength values, whereas their higher daily sleep duration values were comparable with those of the controls.
Our results suggest that daily physical activity and muscle strength were impaired in female cholelithiasis patients when compared with the healthy controls. We suggest that using daily exercises, including not only aerobic but also strength training as lifestyle modifications in cholelithiasis patients, might be helpful for the development of more beneficial illness management strategies.
本研究旨在调查胆结石患者的每日能量消耗、静息代谢率（RMR）、与健康相关的身体素质参数，如最大有氧能力、肌肉力量和柔韧性、肺功能测试（PFT）以及身体成分和体脂分布变化，并将其与健康对照组进行比较。
本研究纳入了30名女性胆结石患者和30名对照者。使用代谢动态心电图监测每日身体活动，并使用阿斯特兰德次极量运动方案估算最大有氧能力。使用生物电阻抗分析仪确定身体成分。还进行了静息代谢率、肺功能测试、力量、柔韧性、周长和皮褶测量。
患者和对照组之间的最大有氧能力、躯干柔韧性、每日中等活动时长、每日剧烈活动时长、总能量消耗、静息代谢率、肺功能测试、瘦体重、肥胖程度和体脂分布值无显著差异。胆结石患者的每日步数、握力和后腿力量值较低，而其较长的每日睡眠时间值与对照组相当。
我们的结果表明，与健康对照组相比，女性胆结石患者的每日身体活动和肌肉力量受损。我们建议，在胆结石患者中采用包括有氧运动和力量训练在内的日常锻炼作为生活方式的改变，可能有助于制定更有益的疾病管理策略。
