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基于荧光共振能量转移的移动自组织分子纳米网络的通信理论分析

A communication theoretical analysis of FRET-based mobile ad hoc molecular nanonetworks.

作者信息

Kuscu Murat, Akan Ozgur B

出版信息

IEEE Trans Nanobioscience. 2014 Sep;13(3):255-66. doi: 10.1109/TNB.2014.2329178. Epub 2014 Jun 30.

Abstract

Nanonetworks refer to a group of nanosized machines with very basic operational capabilities communicating to each other in order to accomplish more complex tasks such as in-body drug delivery, or chemical defense. Realizing reliable and high-rate communication between these nanomachines is a fundamental problem for the practicality of these nanonetworks. Recently, we have proposed a molecular communication method based on Förster Resonance Energy Transfer (FRET) which is a nonradiative excited state energy transfer phenomenon observed among fluorescent molecules, i.e., fluorophores. We have modeled the FRET-based communication channel considering the fluorophores as single-molecular immobile nanomachines, and shown its reliability at high rates, and practicality at the current stage of nanotechnology. In this study, for the first time in the literature, we investigate the network of mobile nanomachines communicating through FRET. We introduce two novel mobile molecular nanonetworks: FRET-based mobile molecular sensor/actor nanonetwork (FRET-MSAN) which is a distributed system of mobile fluorophores acting as sensor or actor node; and FRET-based mobile ad hoc molecular nanonetwork (FRET-MAMNET) which consists of fluorophore-based nanotransmitter, nanoreceivers and nanorelays. We model the single message propagation based on birth-death processes with continuous time Markov chains. We evaluate the performance of FRET-MSAN and FRET-MAMNET in terms of successful transmission probability and mean extinction time of the messages, system throughput, channel capacity and achievable communication rates.

摘要

纳米网络是指一组具有非常基本操作能力的纳米级机器,它们相互通信以完成更复杂的任务,如体内药物递送或化学防御。实现这些纳米机器之间可靠且高速率的通信是这些纳米网络实用性的一个基本问题。最近,我们提出了一种基于福斯特共振能量转移(FRET)的分子通信方法,FRET是在荧光分子(即荧光团)之间观察到的一种非辐射激发态能量转移现象。我们将荧光团视为单分子固定纳米机器,对基于FRET的通信信道进行了建模,并展示了其在高速率下的可靠性以及在当前纳米技术阶段的实用性。在本研究中,我们在文献中首次研究了通过FRET进行通信的移动纳米机器网络。我们引入了两种新型的移动分子纳米网络:基于FRET的移动分子传感器/执行器纳米网络(FRET-MSAN),它是作为传感器或执行器节点的移动荧光团的分布式系统;以及基于FRET的移动自组织分子纳米网络(FRET-MAMNET),它由基于荧光团的纳米发射器、纳米接收器和纳米中继组成。我们基于连续时间马尔可夫链的生灭过程对单消息传播进行建模。我们从消息的成功传输概率和平均消失时间、系统吞吐量、信道容量以及可实现的通信速率等方面评估了FRET-MSAN和FRET-MAMNET的性能。

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