Parmar M K, Freedman L S, Hargreave T B, Tolley D A
MRC Cancer Trials Office, Cambridge, United Kingdom.
J Urol. 1989 Aug;142(2 Pt 1):284-8. doi: 10.1016/s0022-5347(17)38731-1.
With data from 2 large randomized British Medical Research Council studies we identified several factors influencing the recurrence of newly diagnosed superficial bladder cancer. Using multivariate methods to assess the relative importance of these factors we found the most important to be the result of cystoscopy performed 3 months after initial transurethral resection and the number of tumors (single or multiple) at presentation. With these 2 factors we divided the patient population into 3 groups with varying degrees of prognosis. Different followup procedures are proposed for each of these 3 groups.
根据英国医学研究委员会两项大型随机研究的数据,我们确定了几个影响新诊断的浅表性膀胱癌复发的因素。使用多变量方法评估这些因素的相对重要性,我们发现最重要的因素是初次经尿道切除术后3个月进行的膀胱镜检查结果以及就诊时肿瘤的数量(单个或多个)。根据这两个因素,我们将患者群体分为预后程度不同的三组。针对这三组患者分别提出了不同的随访程序。