Institute of Electrical Engineering and Measurement Technology, Department of Sensors and Measurement Technology, Leibniz University Hanover, Appelstr. 9a, Hanover, Germany.
Institute of Electrical Engineering and Measurement Technology, Department of Sensors and Measurement Technology, Leibniz University Hanover, Appelstr. 9a, Hanover, Germany.
J Chromatogr A. 2014 Aug 22;1356:241-8. doi: 10.1016/j.chroma.2014.06.059. Epub 2014 Jun 25.
Identifying the compounds of an unknown gas mixture by using an ion mobility spectrometer (IMS) is a difficult task, because several ion species can be generated in the ionization process. One method to analyze the occurring peaks in an IMS spectrum is coupling an IMS to a mass spectrometer (MS). In our setup we coupled a (3)H drift tube IMS to a Bruker micrOTOF II. Therefore, the detector plate of the IMS is pierced and a transfer capillary is inserted. The ions are transferred via gas flow and electric fields into the MS. The transmission of the ions through the transfer capillary can be shuttered very precisely by increasing the electric potential of the detector generating a repulsive electric field. Thus, it is possible to transfer single ion clouds of generated IMS spectra into the mass spectrometer where a corresponding mass spectrum is generated. In this work we analyze the positive and negative IMS spectra of single analytes as well as gas mixtures and characterize the occurring ion species.
使用离子淌度谱仪（IMS）识别未知气体混合物的化合物是一项艰巨的任务，因为在电离过程中会产生多种离子物种。分析 IMS 光谱中出现的峰的一种方法是将 IMS 与质谱仪（MS）耦合。在我们的设置中，我们将（3）H 漂移管 IMS 与 Bruker micrOTOF II 耦合。因此，IMS 的检测器板被刺穿，并插入一个传输毛细管。离子通过气流和电场传输到 MS 中。通过增加产生排斥电场的检测器的电势，可以非常精确地关闭离子通过传输毛细管的传输，从而可以将生成的 IMS 光谱的单个离子云转移到生成相应质谱的质谱仪中。在这项工作中，我们分析了单一组分以及气体混合物的正离子和负离子 IMS 光谱，并对出现的离子物种进行了表征。
