Akhtar M S, Khan M S
J Pak Med Assoc. 1989 Apr;39(4):107-13.
Blood glucose levels of normal and diabetic rabbits were determined after oral administration of graded doses of three different types of honeys; namely honeys of Apis florea (Small-Bee) and Apis dorsata (Large-Bee) and an adulterated commercial honey. The chemical analysis showed that commercial honey was adulterated with a saturated sucrose solution as it contained lower ash but higher nonreducing sugar levels than the natural ones. Oral administration of pure small or large-bee honeys in 5 ml/kg/doses could not produce a significant (P greater than 0.05) increase in glucose levels in normal and alloxan-diabetic rabbits whereas the adulterated honey significantly raised the blood glucose levels in normal and hyperglycaemic rabbits even at this low dosage. In higher doses of 10 ml/kg and 15 ml/kg body weight, all the three honeys produced a significant (P less than 0.05 or P less than 0.001) rise in blood glucose levels of normal as well as alloxan-diabetic rabbits. It may, therefore, be suggested that pure natural honeys in low doses may be recommended as a source of carbohydrates and even as a sweetening agent in place of sucrose to the human patients suffering from diabetes mellitus (JPMA 39: 107, 1989).
给正常兔子和糖尿病兔子口服三种不同类型蜂蜜的不同剂量后，测定其血糖水平。这三种蜂蜜分别是小蜜蜂（Apis florea）蜂蜜、大蜜蜂（Apis dorsata）蜂蜜和一种掺假的市售蜂蜜。化学分析表明，市售蜂蜜掺有饱和蔗糖溶液，因为其灰分含量低于天然蜂蜜，但非还原糖水平高于天然蜂蜜。以5毫升/千克的剂量给正常兔子和四氧嘧啶诱导的糖尿病兔子口服纯的小蜜蜂蜂蜜或大蜜蜂蜂蜜，不会使血糖水平显著升高（P大于0.05），而即使是低剂量的掺假蜂蜜也会使正常兔子和高血糖兔子的血糖水平显著升高。以10毫升/千克和15毫升/千克体重的更高剂量给药时，所有三种蜂蜜都会使正常兔子和四氧嘧啶诱导的糖尿病兔子的血糖水平显著升高（P小于0.05或P小于0.001）。因此，对于患有糖尿病的人类患者，低剂量的纯天然蜂蜜可作为碳水化合物来源，甚至可作为甜味剂替代蔗糖（《巴基斯坦医学协会杂志》39: 107, 1989）。
