Tashiro H, Nomura Y, Hisamatsu K
Rinsho Hoshasen. 1989 Apr;34(4):443-7.
The results of adjuvant trials conducted from April, 1972 to August, 1978 showed that chemotherapy was more effective to premenopausal patients and endocrine therapy prolonged disease-free survival of postmenopausal patients compared with premenopausal ones. Preliminary analysis of randomized trial now on going suggests that endocrine therapy is best candidate for receptor-positive patients and chemotherapy for receptor-negative patients. Prognostic factors of primary breast cancer was discussed.
1972年4月至1978年8月进行的辅助试验结果表明，化疗对绝经前患者更有效，与绝经前患者相比，内分泌治疗可延长绝经后患者的无病生存期。正在进行的随机试验的初步分析表明，内分泌治疗是受体阳性患者的最佳选择，化疗是受体阴性患者的最佳选择。本文还讨论了原发性乳腺癌的预后因素。
