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动脉瘤性蛛网膜下腔出血综述——重点关注治疗、麻醉、脑血管痉挛的预防及治疗。

Review of aneurysmal subarachnoid hemorrhage--focus on treatment, anesthesia, cerebral vasospasm prophylaxis, and therapy.

作者信息

Lin Bo-Feng, Kuo Chan-Yang, Wu Zhi-Fu

机构信息

Department of Anesthesiology, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan, ROC; Graduate Institute of Medical Science, National Defense Medical Center, Taipei, Taiwan, ROC.

Department of Anesthesiology, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan, ROC; Graduate Institute of Mechanical and Electrical Engineering, National Taipei University of Technology, Taipei, Taiwan, ROC.

出版信息

Acta Anaesthesiol Taiwan. 2014 Jun;52(2):77-84. doi: 10.1016/j.aat.2014.04.005. Epub 2014 Jun 17.

DOI:10.1016/j.aat.2014.04.005
PMID:25016512
Abstract

Aneurysmal subarachnoid hemorrhage (aSAH) is a serious and debilitating condition that leads to the development of many complications, which are followed by mortality and morbidity. As anesthesiologists, we may require to manage aSAH at various settings such as in the perioperative period or in a nonoperative setting such as the neuroradiology suite for diagnostic and therapeutic interventions. Therefore, it is important to understand the pathophysiology of aSAH and anesthetic management for operations and interventions. For decades, early brain injury and cerebral vasospasm have played major roles in the outcome following aSAH. The purpose of this article is to review recent advances and future perspectives in the treatment of aSAH, early brain injury, and cerebral vasospasm.

摘要

动脉瘤性蛛网膜下腔出血(aSAH)是一种严重且使人衰弱的疾病,会引发多种并发症,进而导致死亡和致残。作为麻醉医生,我们可能需要在各种情况下管理aSAH,比如围手术期,或者在非手术环境中,如神经放射科进行诊断和治疗干预时。因此,了解aSAH的病理生理学以及手术和干预的麻醉管理非常重要。几十年来,早期脑损伤和脑血管痉挛在aSAH后的预后中起主要作用。本文旨在综述aSAH、早期脑损伤和脑血管痉挛治疗方面的最新进展和未来展望。

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Risk factors for cerebral vasospasm in patients with aneurysmal subarachnoid hemorrhage.动脉瘤性蛛网膜下腔出血患者发生脑血管痉挛的危险因素。
Open Med (Wars). 2020 Jul 3;15(1):598-604. doi: 10.1515/med-2020-0169. eCollection 2020.
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Stem Cells as a Potential Adjunctive Therapy in Aneurysmal Subarachnoid Hemorrhage.
干细胞作为动脉瘤性蛛网膜下腔出血的一种潜在辅助治疗方法。
J Vasc Interv Neurol. 2016 Jan;8(5):30-7.