Argudo Nuria, Pereira José A, Sancho Juan J, Membrilla Estela, Pons M José, Grande Luis
Servicio de Cirugía General y Digestiva, Hospital Universitari del Mar, Barcelona, Spain; Departament de Cirurgia, Universitat Autònoma de Barcelona, Barcelona, Spain.
Servicio de Cirugía General y Digestiva, Hospital Universitari del Mar, Barcelona, Spain; Department de Ciències Experimentals i de la Salut, Universitat Pompeu Fabra, Barcelona, Spain.
Surgery. 2014 Nov;156(5):1238-44. doi: 10.1016/j.surg.2014.04.035. Epub 2014 Jul 10.
This study was conducted to determine the efficacy and safety of the use of a partially absorbable large pore synthetic prophylactic mesh in emergent midline laparotomies for the prevention of evisceration and incisional hernia.
Retrospective analysis of all patients who underwent an emergency midline laparotomy between January of 2009 and July of 2010 was performed. Patients with complicated ventral hernia repair, postoperative death, and lack of follow-up were excluded.
A total of 266 patients were included. Laparotomies were closed with a running suture of slow-reabsorbable material in 190 patients (Group S), and 50 patients within this group (26.3%) received additional retention sutures. In 76 patients (Group M), an additional partially absorbable lightweight mesh was placed in the Supra-aponeurotic space. Both groups presented similar complication rates (71.1% Group S vs 80.3% Group M, P = .97). There were no differences regarding surgical-site infection rates (17.9% Group S vs 26.3% Group M; P = .13) or postoperative mortality (13.7% Group S vs 18.3% Group M; P = .346). A total of 150 patients completed the follow-up (99 Group S; 51 Group M) at a mean time of 16.7 months. During follow-up, 36 cases of incisional hernia (24%) were diagnosed: 33 (33%) in Group S, whereas there were only three cases (5.9%) in Group M (P = .0001). Mesh removal for chronic infection was not required in any case.
The use of a partially absorbable, lightweight large pore prophylactic mesh in the closure of emergency midline laparotomies is feasible for the prevention of incisional hernia without adding a substantial rate of morbidity to the procedure, even if high contamination or infections are present.
本研究旨在确定在急诊正中剖腹手术中使用部分可吸收的大孔合成预防性补片预防脏器脱出和切口疝的有效性和安全性。
对2009年1月至2010年7月期间接受急诊正中剖腹手术的所有患者进行回顾性分析。排除复杂腹疝修补、术后死亡及失访患者。
共纳入266例患者。190例患者(S组)采用慢吸收材料连续缝合关闭剖腹切口,该组中有50例患者(26.3%)加用了保留缝线。76例患者(M组)在腹直肌后鞘间隙额外放置了一片部分可吸收的轻质补片。两组并发症发生率相似(S组71.1%,M组80.3%,P = 0.97)。手术部位感染率(S组17.9%,M组26.3%;P = 0.13)或术后死亡率(S组13.7%,M组18.3%;P = 0.346)无差异。共有150例患者完成随访(S组99例;M组51例),平均随访时间为16.7个月。随访期间,诊断出36例切口疝(24%):S组33例(33%),而M组仅3例(5.9%)(P = 0.0001)。所有病例均无需因慢性感染取出补片。
在急诊正中剖腹手术关闭切口时使用部分可吸收的轻质大孔预防性补片预防切口疝是可行的,即使存在高度污染或感染,也不会显著增加手术的发病率。