Dean Steven M, Zirwas Matthew
Division of Cardiovascular Medicine, Department of Internal Medicine, The Ohio State University Wexner Medical Center, Columbus, OH.
Division of Dermatology, Department of Internal Medicine, The Ohio State University Wexner Medical Center, Columbus, OH.
Ann Vasc Surg. 2014 Nov;28(8):1935.e13-6. doi: 10.1016/j.avsg.2014.07.005. Epub 2014 Jul 10.
Bier spots represent a benign vascular mottling characterized by multiple irregular white macules along the extensor surfaces of the arms and legs. They have been reported in a variety of diverse conditions with no consistent disease association. We have identified a novel association between these physiologic anemic macules and lower extremity lymphedema. Eleven patients between 23 and 70 years of age (5 male and 6 female) were diagnosed with Bier spots as evidenced by reversible white macules ranging from 3 to 8 mm in diameter on the extensor portions of the feet, ankles, and calves. The thighs were affected as well in 2 morbidly obese subjects. We suspect that these lesions are not uncommon in lymphedema but are simply under-recognized.
比尔斑表现为一种良性血管性斑纹，其特征为沿手臂和腿部伸侧出现多个不规则白色斑疹。在多种不同情况下均有报道，且与疾病无一致关联。我们发现了这些生理性贫血斑疹与下肢淋巴水肿之间的一种新关联。11例年龄在23至70岁之间的患者（5例男性和6例女性）被诊断为比尔斑，足部、脚踝和小腿伸侧可见直径3至8毫米的可逆性白色斑疹。2例病态肥胖患者的大腿也受到影响。我们怀疑这些病变在淋巴水肿中并不罕见，只是未得到充分认识。
