Verhaegh Els M L, Moudrous Walid, Buiting Anton G M, van der Eijk Annemiek A, Tijssen Cees C
St. Elisabeth Ziekenhuis, Tilburg.
Ned Tijdschr Geneeskd. 2014;158:A7033.
Infection with the lymphocytic choriomeningitis virus is a human zoonosis caused by a rodent-borne arenavirus and is often seen in autumn and winter when mice retreat into houses. Infection in humans is acquired after inhalation of aerosols or direct contact with excreta of an infected rodent.
A 37-year-old woman was referred to St. Elisabeth hospital in Tilburg, Netherlands, complaining of severe progressive headache, nausea and vomiting. Three weeks before presentation a mouse had bitten her finger. On neurological examination there were no abnormalities. Cerebrospinal fluid investigations indicated viral meningitis. Immunofluorescence serological testing confirmed the diagnosis of lymphocytic choriomeningitis.
Infection by lymphocytic choriomeningitis virus after contact with rodents can cause viral meningitis. The acquired form of the disease is known to be self-limiting in immunocompetent patients.
淋巴细胞性脉络丛脑膜炎病毒感染是一种由啮齿动物传播的沙粒病毒引起的人畜共患病，常在秋冬季节老鼠进入房屋时出现。人类通过吸入气溶胶或直接接触受感染啮齿动物的排泄物而感染。
一名37岁女性被转诊至荷兰蒂尔堡的圣伊丽莎白医院，主诉严重进行性头痛、恶心和呕吐。就诊前三周，一只老鼠咬了她的手指。神经系统检查未发现异常。脑脊液检查提示病毒性脑膜炎。免疫荧光血清学检测确诊为淋巴细胞性脉络丛脑膜炎。
接触啮齿动物后感染淋巴细胞性脉络丛脑膜炎病毒可导致病毒性脑膜炎。已知在免疫功能正常的患者中，后天感染的这种疾病具有自限性。
