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特应性儿童眼部评估的必要性:一名8岁儿童的双侧角膜水肿

The necessity for ocular assessment in atopic children: bilateral corneal hydrops in an 8 year old.

作者信息

Downie Laura E

机构信息

Department of Optometry and Vision Sciences, The University of Melbourne, Parkville, Victoria, Australia

出版信息

Pediatrics. 2014 Aug;134(2):e596-601. doi: 10.1542/peds.2013-3750. Epub 2014 Jul 14.

Abstract

Acute corneal hydrops is a rare complication of advanced corneal ectasia. This case report describes the clinical course of a child with severe atopy and no previous ocular examination who developed bilateral, acute corneal hydrops, secondary to keratoconus, by 8 years of age. The report demonstrates the rapidity of progression in the pediatric phenotype of the disease. This case also provides an important clinical lesson in highlighting the necessity for children with atopy to be referred for comprehensive ophthalmic examination, even in the apparent absence of visual symptoms, to ensure the timely diagnosis and management of any atopy-associated ocular disease. Prompt referral is particularly essential for pediatric corneal ectasia, in which the rapidity of progression may preclude stabilizing treatments, such as corneal collagen cross-linking, and result in significant childhood visual impairment, as was the case for this child. This case demonstrates the potential for significant ocular involvement in atopic children and identifies scope to enhance current international clinical guidelines relating to the management of childhood atopy through the inclusion of ocular screening for associated disease.

摘要

急性角膜水肿是晚期角膜扩张的一种罕见并发症。本病例报告描述了一名患有严重特应性疾病且此前未进行过眼部检查的儿童的临床病程,该儿童在8岁时因圆锥角膜继发双侧急性角膜水肿。该报告展示了该疾病儿童表型的进展速度。本病例还提供了一个重要的临床教训,即强调即使在明显没有视觉症状的情况下,特应性儿童也有必要转诊进行全面眼科检查,以确保及时诊断和管理任何与特应性相关的眼部疾病。及时转诊对于儿童角膜扩张尤为重要,因为其进展速度可能使诸如角膜胶原交联等稳定治疗无法实施,并导致严重的儿童视力损害,本病例中的儿童就是如此。本病例证明了特应性儿童眼部严重受累的可能性,并确定了通过纳入相关疾病的眼部筛查来加强当前关于儿童特应性疾病管理的国际临床指南的范围。

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