在一项使用胰岛细胞产品的试点研究中，运用BacT/alert系统快速检测微生物污染情况。
Use of the BacT/alert system for rapid detection of microbial contamination in a pilot study using pancreatic islet cell products.
作者信息
Murray Laura, McGowan Neil, Fleming John, Bailey Laura
机构信息
Donation Testing Department, Scottish National Blood Transfusion Service, Glasgow, Scotland.
SNBTS Cell Therapy Development Centre, Scottish National Blood Transfusion Service, The University of Edinburgh, Edinburgh bioQuarter, Edinburgh, Scotland.
出版信息
J Clin Microbiol. 2014 Oct;52(10):3769-71. doi: 10.1128/JCM.00447-14. Epub 2014 Jul 16.
Abstract
At the Islet Isolation Laboratory of the Scottish National Blood Transfusion Service, manual sterility testing data show that contamination rates are 57.7% for pancreas transport fluid, 4.3% for postpurification islet samples, and 0% for pretransplant islet samples. This pilot study presents the BacT/Alert System as an alternative to manual testing to provide more rapid and sensitive sterility results for islet cell products.
摘要
在苏格兰国家血液输血服务中心的胰岛分离实验室，人工无菌检测数据显示，胰腺运输液的污染率为57.7%，纯化后胰岛样本的污染率为4.3%，移植前胰岛样本的污染率为0%。这项初步研究介绍了BacT/Alert系统，作为人工检测的替代方法，可为胰岛细胞产品提供更快速、灵敏的无菌检测结果。
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