叠氮胸苷（AZT）对艾滋病相关综合征和艾滋病患者P24抗原水平的影响。
Effect of azidothymidine (AZT) on P24 antigen levels in patients with AIDS-related complex and AIDS.
作者信息
Reddy M M, McKinley G, Englard A, Grieco M H
机构信息
R.A. Cooke Institute of Allergy, St. Luke's-Roosevelt Hospital Center, New York, New York 10019.
出版信息
J Clin Lab Anal. 1989;3(4):199-201. doi: 10.1002/jcla.1860030402.
Circulating HIV P24 antigen levels at baseline and following AZT therapy were measured in 9 patients with ARC and 11 patients with AIDS. Eight of these patients had no detectable levels of P24. The P24 antigen levels in the remaining 12 patients decreased significantly after AZT treatment. Following discontinuation of AZT treatment in 2 patients, the P24 antigen levels went up. These results clearly demonstrate the efficacy of AZT in reducing P24 antigen levels in circulation.
对9名患艾滋病相关综合征（ARC）的患者和11名艾滋病患者在基线时及接受齐多夫定（AZT）治疗后，检测其循环血中HIV P24抗原水平。这些患者中有8名检测不到P24水平。其余12名患者的P24抗原水平在接受AZT治疗后显著下降。在2名患者停止AZT治疗后，P24抗原水平上升。这些结果清楚地证明了AZT在降低循环血中P24抗原水平方面的疗效。
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