Vlahovic Zoran, Markovic Aleksa, Golubovic Mileta, Scepanovic Miodrag, Kalanovic Milena, Djinic Ana
Department of Dental Medicine, Faculty of Medical Science, University of Priština, Kosovska Mitrovica, Serbia.
School of Dentistry, University of Belgrade, Belgrade, Serbia.
Clin Oral Implants Res. 2015 Nov;26(11):1309-14. doi: 10.1111/clr.12456. Epub 2014 Jul 14.
The aim of this study was comparing the effect of flapless vs. flap technique of implant placement on inflammation degree of peri-implant soft tissue, through histopathological analysis.
The experiment was conducted on five domestic pigs. Nine weeks after tooth extraction, implants were installed. Each animal received six implants in mandible. According to split-mouth design, randomly one side was used for flapless technique using mini-incision, while on the other side, flap was raised. After 7, 14, 21, 28, and 90 days, the experimental animals were sacrificed. Samples for histopathological analyzes were taken from the buccal side of peri-implant mucosa next to the neck of implants, from three levels. The degree of inflammatory response in the peri-implant soft tissue was estimated through ordinal scores from 0 to 3.
In the flap group Score 3 indicating high degree of inflammation was present from day 7 to day 21, in contrast to flapless group where Score 3 was not recorded during the entire follow-up. Three months after implantation, there were no signs of inflammation neither around flap nor around flapless implants.
Flapless surgical implantation technique using mini-incision decreases peri-implant soft tissue inflammatory reaction compared with flap surgery.
本研究旨在通过组织病理学分析，比较不翻瓣与翻瓣种植技术对种植体周围软组织炎症程度的影响。
对5头家猪进行实验。拔牙9周后植入种植体。每只动物在下颌植入6枚种植体。根据双侧对照设计，随机选择一侧采用小切口不翻瓣技术，另一侧翻瓣。在7、14、21、28和90天后，处死实验动物。从种植体颈部旁种植体周围黏膜的颊侧三个层面采集组织病理学分析样本。通过0至3的序贯评分评估种植体周围软组织的炎症反应程度。
翻瓣组在第7天至第21天出现3分表示高度炎症，而不翻瓣组在整个随访期间未记录到3分。植入3个月后，翻瓣和不翻瓣种植体周围均无炎症迹象。
与翻瓣手术相比，采用小切口的不翻瓣手术种植技术可减少种植体周围软组织的炎症反应。
