免疫功能低下宿主反复感染后对多重耐药肺炎克雷伯菌进行肠道去污处理。
Intestinal decontamination of multidrug-resistant Klebsiella pneumoniae after recurrent infections in an immunocompromised host.
作者信息
Kronman Matthew P, Zerr Danielle M, Qin Xuan, Englund Janet, Cornell Cathy, Sanders Jean E, Myers Jeffrey, Rayar Jaipreet, Berry Jessica E, Adler Amanda L, Weissman Scott J
机构信息
Department of Pediatrics, University of Washington, Seattle, WA, USA; Division of Infectious Diseases, University of Washington, Seattle, WA, USA; Center for Clinical and Translational Research, Seattle Children's Hospital Research Institute, Seattle, WA, USA.
Department of Pediatrics, University of Washington, Seattle, WA, USA; Division of Infectious Diseases, University of Washington, Seattle, WA, USA; Center for Clinical and Translational Research, Seattle Children's Hospital Research Institute, Seattle, WA, USA.
出版信息
Diagn Microbiol Infect Dis. 2014 Sep;80(1):87-9. doi: 10.1016/j.diagmicrobio.2014.06.006. Epub 2014 Jun 21.
Abstract
Multidrug-resistant (MDR) Enterobacteriaceae infections are associated with increased morbidity. We describe a 20-year-old hematopoietic cell transplantation recipient with recurrent MDR Klebsiella pneumoniae infection, prolonged intestinal colonization, and subsequent intestinal decontamination. Further study should evaluate stool surveillance, molecular typing, and fecal microbiota transplantation for patients with intestinal MDR Enterobacteriaceae carriage.
摘要
多重耐药（MDR）肠杆菌科感染与发病率增加相关。我们描述了一名20岁的造血细胞移植受者，其反复发生多重耐药肺炎克雷伯菌感染、肠道定植时间延长以及随后的肠道去污。进一步的研究应评估肠道携带多重耐药肠杆菌科细菌患者的粪便监测、分子分型和粪便微生物群移植。
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