Collins Sean, Storrow Alan B, Albert Nancy M, Butler Javed, Ezekowitz Justin, Felker G Michael, Fermann Gregory J, Fonarow Gregg C, Givertz Michael M, Hiestand Brian, Hollander Judd E, Lanfear David E, Levy Phillip D, Pang Peter S, Peacock W Frank, Sawyer Douglas B, Teerlink John R, Lenihan Daniel J
Nashville Veterans Affairs Medical Center and Vanderbilt University, Nashville, Tennessee.
Vanderbilt University, Nashville, Tennessee.
J Card Fail. 2015 Jan;21(1):27-43. doi: 10.1016/j.cardfail.2014.07.003. Epub 2014 Jul 18.
Heart failure (HF) afflicts nearly 6 million Americans, resulting in one million emergency department (ED) visits and over one million annual hospital discharges. An aging population and improved survival from cardiovascular diseases is expected to further increase HF prevalence. Emergency providers play a significant role in the management of patients with acute heart failure (AHF). It is crucial that emergency physicians and other providers involved in early management understand the latest developments in diagnostic testing, therapeutics and alternatives to hospitalization. Further, clinical trials must be conducted in the ED in order to improve the evidence base and drive optimal initial therapy for AHF. Should ongoing and future studies suggest early phenotype-driven therapy improves in-hospital and post-discharge outcomes, ED treatment decisions will need to evolve accordingly. The potential impact of future studies which incorporate risk-stratification into ED disposition decisions cannot be underestimated. Predictive instruments that identify a cohort of patients safe for ED discharge, while simultaneously addressing barriers to successful outpatient management, have the potential to significantly impact quality of life and resource expenditures.
心力衰竭(HF)折磨着近600万美国人,导致100万人次急诊就诊以及每年超过100万次出院。预计人口老龄化和心血管疾病存活率的提高将进一步增加HF的患病率。急诊医护人员在急性心力衰竭(AHF)患者的管理中发挥着重要作用。至关重要的是,参与早期管理的急诊医生和其他医护人员要了解诊断检测、治疗方法以及住院替代方案的最新进展。此外,必须在急诊科开展临床试验,以改善证据基础并推动针对AHF的最佳初始治疗。如果正在进行的和未来的研究表明早期表型驱动治疗可改善住院和出院后结局,那么急诊治疗决策将需要相应地发展。将风险分层纳入急诊处置决策的未来研究的潜在影响不可低估。能够识别出适合急诊出院的患者群体,同时解决成功门诊管理障碍的预测工具,有可能显著影响生活质量和资源支出。