血管异常综述：遗传学和常见综合征。
A review of vascular anomalies: genetics and common syndromes.
机构信息
Division of Plastic Surgery, Baylor College of Medicine, Houston, Texas.
出版信息
Semin Plast Surg. 2014 May;28(2):64-8. doi: 10.1055/s-0034-1376261.
Abstract
Vascular tumors and malformations are unique in that affected cells exhibit disrupted angiogenesis. The current treatment options often yield suboptimal results. New insight into the genetics and molecular basis of vascular anomalies may pave the way for potential development of targeted therapy. The authors review the genetic and molecular basis of vascular anomalies and common associated syndromes.
摘要
血管肿瘤和畸形的独特之处在于受影响的细胞表现出血管生成的破坏。目前的治疗选择往往产生不理想的结果。对血管异常的遗传和分子基础的新认识可能为靶向治疗的潜在发展铺平道路。作者回顾了血管异常和常见相关综合征的遗传和分子基础。
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