Davies John S, Poole Chris D, Feldschreiber Peter
Department of Endocrinology, University Hospital of Wales, Cardiff, CF14 4XJ, UK.
Br J Clin Pharmacol. 2014 Dec;78(6):1257-63. doi: 10.1111/bcp.12472.
Vitamin D is a particularly important sterol hormone and its effects beyond bone are increasingly recognized. Over the last decade clinical interest has grown in vitamin D, with increased recognition of deficiency and hence increased prescribing of vitamin D products. However, the increased prescription of vitamin D has generally been met with unlicensed vitamin D products which potentially expose the patient to clinical risk. This review discusses the issues relating to the clinical use of unlicensed vitamin D products, safety concerns that may arise from this, as well as discussing the medico-legal responsibilities of the prescriber and dispenser.
维生素D是一种特别重要的甾醇类激素,其对骨骼以外的作用越来越受到认可。在过去十年中,临床对维生素D的兴趣有所增加,对维生素D缺乏的认识增多,因此维生素D产品的处方量也有所增加。然而,维生素D处方量的增加通常伴随着未经许可的维生素D产品,这可能会使患者面临临床风险。本综述讨论了与未经许可的维生素D产品临床使用相关的问题、可能由此产生的安全问题,以及处方者和配药者的医疗法律责任。