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中国哮喘患者焦虑和抑郁的患病率。

The prevalence of anxiety and depression in Chinese asthma patients.

作者信息

Liu Shigang, Wu Ruohan, Li Lei, Liu Li, Li Guoqin, Zhang Xia, Guo Yuyan, Wang Yinghui, Zhang Hong, Li Guangxi, Li Hui

机构信息

Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, China.

Beijing University of Chinese Medicine, Beijing, China.

出版信息

PLoS One. 2014 Jul 23;9(7):e103014. doi: 10.1371/journal.pone.0103014. eCollection 2014.

Abstract

It is well documented that the psychiatric disorders are common in Asthma patients in China while the studies on the relationship between asthma control and psychological disorder are comparatively rare. We therefore performed a cross-sectional study on asthmatic outpatients in one Chinese tertiary center to investigate the correlation among asthma, anxiety and depression. Demographic data, anxiety and depression scores, the level of asthma control were collected in 261 patients. All patients were evaluated with Asthma Control Test (ACT), Self-Rating Anxiety Scale (SAS) and Self-rating depression scale (SDS) questionnaires. A multivariate analysis was performed to investigate the relationship between asthma control and psychological disorder. The result showed that 31 asthma patients had anxiety symptom while thirty-five asthma patients had depression. One hundred and ninety-two asthma patients were well controlled and 69 patients were not. The study found a negative correlation between ACT and SAS(r = -0.231, p<0.001) as well as ACT and SDS(r = -0.23, p<0.001) and depression (OR: 12.295, 95%CI: [5.374-28.128], p<0.001) were both independently associated with poor asthma control. We concluded that Asthma control is greatly affected by psychological disorder in Chinese patients.

摘要

有充分的文献记载,在中国哮喘患者中精神疾病很常见,而关于哮喘控制与心理障碍之间关系的研究相对较少。因此,我们在中国一家三级中心对哮喘门诊患者进行了一项横断面研究,以调查哮喘、焦虑和抑郁之间的相关性。收集了261例患者的人口统计学数据、焦虑和抑郁评分以及哮喘控制水平。所有患者均通过哮喘控制测试(ACT)、自评焦虑量表(SAS)和自评抑郁量表(SDS)问卷进行评估。进行多变量分析以研究哮喘控制与心理障碍之间的关系。结果显示,31例哮喘患者有焦虑症状,35例哮喘患者有抑郁症状。192例哮喘患者控制良好,69例患者控制不佳。研究发现ACT与SAS之间呈负相关(r = -0.231,p<0.001),ACT与SDS之间也呈负相关(r = -0.23,p<0.001),并且抑郁(OR:12.295,95%CI:[5.374 - 28.128],p<0.001)均与哮喘控制不佳独立相关。我们得出结论,在中国患者中,心理障碍对哮喘控制有很大影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6fdb/4108371/8d92df6b0143/pone.0103014.g001.jpg

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