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一种基于热活化延迟荧光(TBET)的用于Fe³⁺的荧光比率化学传感器及其在活细胞中的应用。

A fluorescence ratiometric chemosensor for Fe³⁺ based on TBET and its application in living cells.

作者信息

Wang Cuicui, Zhang Di, Huang Xiaoyan, Ding Peigang, Wang Zhenji, Zhao Yufen, Ye Yong

机构信息

Phosphorus Chemical Engineering Research Center of Henan Province, The College of Chemistry and Molecular Engineering, Zhengzhou University, Zhengzhou 450052, China.

School of Pharmaceutical Science, Zhengzhou University, Zhengzhou, China.

出版信息

Talanta. 2014 Oct;128:69-74. doi: 10.1016/j.talanta.2014.03.073. Epub 2014 Apr 23.

Abstract

Based on a through bond energy transfer (TBET) between rhodamine and naphthalimide fluorophores, a fluorescent ratiometric chemosensor L was designed and prepared for highly selective detection of Fe(3+) in aqueous solution and in living EC109 cells. These significant changes in the fluorescence color could be used for naked-eye detection. The reversibility established the potential of the probe as chemosensor for Fe(3+) detection.

摘要

基于罗丹明与萘二甲酰亚胺荧光团之间的穿键能量转移(TBET),设计并制备了一种荧光比率化学传感器L,用于在水溶液和活的EC109细胞中高选择性地检测Fe(3+)。荧光颜色的这些显著变化可用于裸眼检测。这种可逆性确立了该探针作为检测Fe(3+)的化学传感器的潜力。

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