Cornea Unit, Institut de Microcirugia Ocular, Universidad Autónoma de Barcelona, Cerdanyola del Vallès, Spain.
Cornea. 2014 Sep;33(9):985-7. doi: 10.1097/ICO.0000000000000195.
The aim of this study was to report progressive corneal clearance and endothelial cell repopulation after a Descemet membrane endothelial keratoplasty graft that was partially folded over on itself in a pseudophakic patient without endothelial dystrophy.
Retrospective case report.
A 75-year-old man without Fuchs dystrophy underwent cataract extraction on his right eye in 2007, and 5 years later, Descemet membrane endothelial keratoplasty was performed for pseudophakic edema in the same eye at another center. On presentation at our institution, a graft that is partially folded over on itself was observed in the right eye, leaving about 2/3 of donor endothelium correctly exposed. The graft was only attached in the lower part of the cornea. We observed progressive clearance of the entire cornea within 7 months with reendothelialization of the entire cornea. Good visual acuity was achieved, with no evidence of recurrent corneal edema.
Endothelial cell migration and repopulation in the presence of a folded attached endothelium graft may occur, resulting in corneal clearance and improved visual outcome. This could happen in patients with pseudophakic edema without congenital endothelial dystrophy.
本研究旨在报告在一名无内皮层营养不良的白内障术后患者中,部分对折的穿透性角膜移植术后,角膜的渐进性清除和内皮细胞再植的情况。
回顾性病例报告。
一名 75 岁男性,无 Fuchs 营养不良,于 2007 年右眼行白内障摘除术,5 年后,右眼因假性囊泡性水肿在另一中心行穿透性角膜移植术。在我们机构就诊时,发现右眼的移植片部分对折,大约 2/3 的供体内皮细胞正确暴露。移植片仅在下半部分角膜附着。我们观察到整个角膜在 7 个月内逐渐清除,整个角膜重新内皮化。视力良好,无复发性角膜水肿的证据。
在附着的对折内皮移植物存在的情况下,内皮细胞的迁移和再植可能会发生,导致角膜清除和视力改善。这可能发生在无先天性内皮层营养不良的白内障术后假性囊泡性水肿患者中。