Richter Claus-Peter, Young Hunter
Department of Otolaryngology, Northwestern University, 303 E. Chicago Ave, Searle 12-561, Chicago, IL 60611, USA ; Department of Biomedical Engineering, Northwestern University, 2145 Sheridan Road, Tech E310, Evanston, IL 60208, USA ; The Hugh Knowles Center, Department of Communication Sciences and Disorders, Northwestern University, 2240 Campus Drive, Evanston, IL 60208, USA.
Department of Otolaryngology, Northwestern University, 303 E. Chicago Ave, Searle 12-561, Chicago, IL 60611, USA.
Proc SPIE Int Soc Opt Eng. 2013 Mar 8;8656:85655U. doi: 10.1117/12.2013847.
Responses of units in the central nucleus of the inferior colliculus of the guinea pig were recorded with tungsten electrodes. The set of data presented here is limited to high stimulus levels. The effect of changing the modulation frequency and the modulation depth was explored for acoustic and laser stimuli. The selected units responded to sinusoidal amplitude modulated (AM) tones, AM trains of clicks, and AM trains of laser pulses with a modulation of their spike discharge. At modulation frequencies of 20 Hz, some units tended to respond with 40 Hz to the acoustic stimuli, but only at 20 Hz for the trains of laser pulses. For all modes of stimulation the responses revealed a dominant response to the first cycle of the modulation, with decreasing number of action potential during successive cycles. While amplitude modulated tone bursts and amplitude modulated trains of acoustic clicks showed similar patterns, the response to trains of laser pulses was different.
用钨电极记录豚鼠下丘中央核神经元的反应。这里呈现的数据集仅限于高刺激水平。研究了改变调制频率和调制深度对声音和激光刺激的影响。所选神经元对正弦调幅（AM）音调、AM短声序列以及AM激光脉冲序列产生反应，其放电活动会随调制而变化。在20Hz的调制频率下，一些神经元对声音刺激倾向于以40Hz做出反应，但对激光脉冲序列仅在20Hz时做出反应。对于所有刺激模式，反应均显示对调制的第一个周期有主导反应，在后续周期中动作电位数量逐渐减少。虽然调幅音爆和调幅短声序列表现出相似的模式，但对激光脉冲序列的反应有所不同。
