Vitiello Giuseppe
Dipartimento di Fisica "E.R. Caianiello", Università di Salerno, Fisciano, I-84084 Salerno, Italy; Istituto Nazionale di Fisica Nucleare, Gruppo Collegato di Salerno, Fisciano, I-84084 Salerno, Italy.
Curr Opin Neurobiol. 2015 Apr;31:7-12. doi: 10.1016/j.conb.2014.07.017. Epub 2014 Jul 30.
The problem of the transition from the molecular and cellular level to the macroscopic level of observed assemblies of myriads of neurons is the subject addressed in this report. The great amount of detailed information available at molecular and cellular level seems not sufficient to account for the high effectiveness and reliability observed in the brain macroscopic functioning. It is suggested that the dissipative many-body model and thermodynamics might offer the dynamical frame underlying the rich phenomenology observed at microscopic and macroscopic level and help in the understanding on how to fill the gap between the bio-molecular and cellular level and the one of brain macroscopic functioning.
本报告探讨了从无数神经元的分子和细胞层面过渡到宏观层面这一问题。分子和细胞层面可获取的大量详细信息似乎不足以解释大脑宏观功能中所观察到的高效性和可靠性。有人提出,耗散多体模型和热力学可能为微观和宏观层面所观察到的丰富现象学提供动力学框架,并有助于理解如何填补生物分子和细胞层面与大脑宏观功能层面之间的差距。