Ballon Nicolas, Brunault Paul, Cortese Samuele
CHRU de Tours, Clinique Psychiatrique Universitaire, Tours, France CHRU de Tours, Équipe de Liaison et de Soins en Addictologie, Tours, France Université François Rabelais de Tours, Tours, France UMR INSERM U930 ERL, Tours, France.
CHRU de Tours, Clinique Psychiatrique Universitaire, Tours, France CHRU de Tours, Équipe de Liaison et de Soins en Addictologie, Tours, France Université François Rabelais de Tours, Département de Psychologie, EA 2114, Psychologie des Ages de la Vie, Tours, France.
J Atten Disord. 2015 Apr;19(4):335-42. doi: 10.1177/1087054714543651. Epub 2014 Aug 1.
To compare measures of sensation seeking in a clinical group of cocaine-dependent (CD) patients with and without a history of probable childhood ADHD and in non-cocaine-dependent (NCD) healthy volunteers.
Patients (n = 75; 42 with and 33 without probable childhood ADHD) and comparisons (n = 84) were assessed with the Diagnostic Interview for Genetic Studies, the Wender Utah Rating Scale for childhood ADHD, and the Zuckerman Seeking Sensation Scale.
We found significantly higher prevalence rates of probable childhood ADHD in CD versus NCD (p < .001). The mean total scores of sensation seeking were significantly higher in CD versus NCD participants (p < .001) as well as in CD patients with versus those without a probable history of childhood ADHD (p < .001).
Our study sets the basis for longitudinal investigation assessing whether the persistence of high level of sensation seeking in adults with childhood ADHD contributes to the transition to cocaine dependence.
比较有或无童年期注意缺陷多动障碍（ADHD）病史的可卡因依赖（CD）临床患者组与非可卡因依赖（NCD）健康志愿者的感觉寻求测量指标。
对患者（n = 75；42名有童年期ADHD可能，33名无童年期ADHD可能）和对照组（n = 84）进行遗传研究诊断访谈、童年期ADHD的温德尔犹他评定量表和朱克曼感觉寻求量表评估。
我们发现，与NCD组相比，CD组童年期ADHD可能的患病率显著更高（p < .001）。CD组参与者的感觉寻求平均总分显著高于NCD组（p < .001），有童年期ADHD可能病史的CD患者与无此病史的CD患者相比也是如此（p < .001）。
我们的研究为纵向调查奠定了基础，该调查旨在评估童年期ADHD的成年人中持续存在的高水平感觉寻求是否会导致向可卡因依赖的转变。
