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[早产儿视网膜病变中的视网膜血管]

[Retinal vessels in retinopathy of prematurity].

作者信息

Tereshchenko A V, Belyĭ Iu A, Isaev S V, Trifanenkova I G

出版信息

Vestn Oftalmol. 2014 May-Jun;130(3):26-31.

Abstract

PURPOSE

To define diagnostic morphometric parameters of central fundus and peripheral retinal vessels that characterize different types of retinopathy of prematurity (ROP) course.

MATERIAL AND METHODS

A total of 155 premature infants (310 eyes) with stage I, II, and III ROP were assessed as they were undergoing treatment in the Kaluga branch of "Eye Microsurgery" complex during 2010-2012. Patients with the same stage of the disease were divided into two groups according to the type of ROP course (type 1--ROP with low risk of progression, type 2--ROP with high risk of progression). Original ROP-MORPHOMETRY software was used for morphometric analysis of digital images of the fundus taken with RetCam 120 and RetCam 3 through a 130 degree lens.

RESULTS

Regardless the stage of the disease, larger diameter of retinal vessels and higher tortuosity index was found in type 2 ROP (favorable) as compared with type 1 ROP (unfavorable). An observation was made, that the father from the central fundus the narrower became the vessels of both nasal and temporal arcades.

CONCLUSION

The obtained quantitative morphometric data can help to clearly determine the risk of progression at any stage of ROP.

摘要

目的

确定表征不同类型早产儿视网膜病变(ROP)病程的中央眼底和周边视网膜血管的诊断形态测量参数。

材料与方法

2010 - 2012年期间,对在“眼科显微手术”联合体卡卢加分部接受治疗的155例患有I、II和III期ROP的早产儿(310只眼)进行了评估。根据ROP病程类型(1型 - 进展风险低的ROP,2型 - 进展风险高的ROP)将处于相同疾病阶段的患者分为两组。使用原始的ROP - 形态测量软件,通过130度镜头对用RetCam 120和RetCam 3拍摄的眼底数字图像进行形态测量分析。

结果

无论疾病处于何阶段,与1型ROP(不良型)相比,2型ROP(良好型)中视网膜血管直径更大且迂曲指数更高。观察到,离中央眼底越远,鼻侧和颞侧视网膜血管弓的血管越窄。

结论

所获得的定量形态测量数据有助于明确确定ROP任何阶段的进展风险。

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