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用于评估结构重塑的桡动脉内膜中层厚度高分辨率超声测量的验证

Validation of High-Resolution Ultrasound Measurements of Intima-Media Thickness of the Radial Artery for the Assessment of Structural Remodeling.

作者信息

Stegemann Emilia, Sansone R, Stegemann B, Kelm M, Heiss C

机构信息

Medical Faculty, University Düsseldorf, Düsseldorf, Germany

Medical Faculty, University Düsseldorf, Düsseldorf, Germany.

出版信息

Angiology. 2015 Jul;66(6):574-7. doi: 10.1177/0003319714544699. Epub 2014 Aug 5.

DOI:10.1177/0003319714544699
PMID:25100749
Abstract

Radial artery (RA) intima-media thickness (IMT) could be used to study short- and long-term structural vascular adaptation following transradial cardiac catheterization. We aimed at assessing the reliability and reproducibility of RA-IMT measurement. Using high-resolution ultrasound, we studied RA-IMT in 17 patients, who underwent transradial catheterization via the right RA 1 to 12 months before. Radial artery intima-media thickness was measured in both arms, with the left RA as control. Repeated measurements were performed by 2 examiners and offline analyses were performed by independent blinded interpreters. Radial artery intima-media thickness was highly reliable with an interclass correlation coefficient (ICC) of 0.911 [0.870-0.939], a high examiner (ICCexaminer 0.910 [0.883-0.931]), and interpreter agreement (ICCinterpreter 0.963 [0.954-0.971]). Intima-media thickness at the radial access site was significantly increased compared with the contralateral RA (0.30 ± 0.056 vs 0.41 ± 0.055 mm, P < .00001). Radial artery intima-media thickness can be measured reliably using high-resolution ultrasound. Initial data suggest that transradial catheterization leads to long-term structural adaption processes.

摘要

桡动脉(RA)内膜中层厚度(IMT)可用于研究经桡动脉心脏导管插入术后血管结构的短期和长期适应性变化。我们旨在评估RA-IMT测量的可靠性和可重复性。我们使用高分辨率超声对17例患者的RA-IMT进行了研究,这些患者在1至12个月前经右侧RA接受了桡动脉导管插入术。测量了双侧手臂的桡动脉内膜中层厚度,以左侧RA作为对照。由2名检查者进行重复测量,并由独立的盲法解释者进行离线分析。桡动脉内膜中层厚度具有高度可靠性,组内相关系数(ICC)为0.911[0.870-0.939],检查者间一致性高(ICC检查者0.910[0.883-0.931]),解释者间一致性也高(ICC解释者0.963[0.954-0.971])。桡动脉穿刺部位的内膜中层厚度与对侧RA相比显著增加(0.30±0.056 vs 0.41±0.055mm,P<.00001)。使用高分辨率超声能够可靠地测量桡动脉内膜中层厚度。初步数据表明,经桡动脉导管插入术会导致长期的结构适应性变化。

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