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口服万古霉素治疗艰难梭菌感染后发生耐万古霉素无害梭菌血症。

Vancomycin-resistant Clostridium innocuum bacteremia following oral vancomycin for Clostridium difficile infection.

作者信息

Hung Yuan-Pin, Lin Hsiao-Ju, Wu Chi-Jung, Chen Po-Lin, Lee Jen-Chieh, Liu Hsiao-Chieh, Wu Yi-Hui, Yeh Fang Hao, Tsai Pei-Jane, Ko Wen-Chien

机构信息

Departments of Internal Medicine, Tainan Hospital, Ministry of Health & Welfare, Tainan, Taiwan; Department of Internal Medicine, National Cheng Kung University Hospital and Medical College, Tainan, Taiwan; Graduate Institute of Clinical Medicine, National Health Research Institutes, Tainan, Taiwan.

Graduate Institute of Clinical Medicine, National Health Research Institutes, Tainan, Taiwan; National Institute of Infectious Diseases and Vaccinology, National Health Research Institutes, Tainan, Taiwan.

出版信息

Anaerobe. 2014 Dec;30:24-6. doi: 10.1016/j.anaerobe.2014.07.009. Epub 2014 Aug 5.

Abstract

An 85 year-old male initially admitted for septic shock due to urinary tract infection experienced Clostridium difficile-associated diarrhea during hospitalization and was treated by oral vancomycin. His clinical course was complicated by cytomegalovirus colitis and then vancomycin-resistant Clostridium innocuum bacteremia, which was cured by uneventfully parenteral piperacillin-tazobactam therapy.

摘要

一名85岁男性因尿路感染导致脓毒症休克入院,住院期间出现艰难梭菌相关性腹泻,接受口服万古霉素治疗。其临床病程因巨细胞病毒结肠炎而复杂化,随后又出现对万古霉素耐药的无害梭菌血症,通过静脉注射哌拉西林-他唑巴坦治疗顺利治愈。

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